Structural and morphological characterization of silver nanoparticles intruded mineral trioxide aggregate admixture as a chair-side restorative medicament: an in vitro experimental study.

IF 1.5
Restorative Dentistry & Endodontics Pub Date : 2025-08-01 Epub Date: 2025-08-08 DOI:10.5395/rde.2025.50.e30
H Murali Rao, Rajkumar Krishnan, Chitra Shivalingam, Ramya Ramadoss
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Abstract

Objectives: The aim of this study was to create a rapid admixture of mineral trioxide aggregate (MTA) and silver nanoparticles (AgNPs) for chairside use in clinical settings to remediate the challenges associated with root canal treatment and pulp capping.

Methods: Synthesized AgNPs at ratios of 10 and 25% were added to commercially available MTA to create an admixture. The admixture was subjected to structural and morphological assessment using X-ray diffraction analysis (XRD), Fourier transform infrared (FT-IR) analysis, Raman spectroscopy, and scanning electron microscopy. Antioxidant activity was measured using the hydroxyl radical scavenging assay. A significance level of 0.05 was applied to determine statistical differences.

Results: The addition of AgNPs decreased the carbonate peak intensity in XRD and FT-IR. The rod-like morphology of MTA was changed to a flake-like morphology with the addition of AgNPs. Antibacterial efficacy enhanced proportionally with the augmentation of AgNPs concentration.

Conclusions: The creation of rapid admixture of MTA and AgNPs during chairside use in clinical settings can deliver beneficial characteristics of enhanced morphological features favoring mineralization and profound antibacterial effects to overcome the challenges associated with root canal treatment and pulp capping.

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银纳米颗粒侵入三氧化二矿骨料外加剂作为椅子侧修复药物的结构和形态表征:体外实验研究。
目的:本研究的目的是创造一种矿物三氧化物聚集体(MTA)和银纳米粒子(AgNPs)的快速混合物,用于临床设置椅子旁,以修复与根管治疗和牙髓盖盖相关的挑战。方法:以10%和25%的比例将合成的AgNPs添加到市售的MTA中形成混合物。采用x射线衍射分析(XRD)、傅里叶变换红外(FT-IR)分析、拉曼光谱和扫描电镜对混合物进行了结构和形态评价。采用羟基自由基清除法测定抗氧化活性。采用0.05的显著性水平来确定统计学差异。结果:AgNPs的加入降低了XRD和FT-IR中的碳酸盐峰强度。加入AgNPs后,MTA的棒状形态变为片状形态。抗菌效果随AgNPs浓度的增加成比例增强。结论:MTA和AgNPs在临床使用时的快速混合物可以提供有利于矿化的增强形态学特征和深刻的抗菌效果,以克服与根管治疗和牙髓盖盖相关的挑战。
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来源期刊
CiteScore
0.20
自引率
0.00%
发文量
35
审稿时长
12 weeks
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