Mohammad Yahia Alzahrani, Mohammad Sayed Abdelghaffar, Tariq Hashim Adlan
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引用次数: 0
Abstract
Background: Approximately 15% of fine-needle aspiration biopsy (FNAB) procedures are considered inconclusive, caused by various factors such as nodule characteristics, level of expertise, and needle size. Since needle size may play a crucial role in both adequacy of FNAB samples and reduction of complications, our objective was to compare cytology specimen adequacy, blood contamination, and findings in thyroid nodules and lymph nodes using 22- and 25-gauge needles in fine-needle aspiration (FNA).
Materials and methods: A retrospective comparative cohort study was conducted at King Fahad Specialist Hospital, Saudi Arabia. Data were collected from electronic medical records between January and December 2021. An ultrasound-guided FNA procedure was performed. Each nodule was sampled in three passes using a 25-gauge and a 22-gauge fine needle. A total of 153 (115 with thyroid nodules; 57 with 22-gauge and 58 with 25-gauge and 38 with lymph nodes; 21 with 22-gauge and 17 with 25-gauge) cases were included. Data analysis was done using SPSS version 26. All cases were divided into two groups: 22-gauge or 25-gauge needle group. Chi-square test and binary logistic regression were used for comparison.
Results: No significant differences were found. Adequacy rates were 93.9% for thyroid and 97.4% for lymph node samples (P = 0.68). Conclusive diagnoses were 97.4% for thyroid and 94.7% for lymph nodes (P = 0.137). Bloody samples were more frequent in lymph nodes (23.7%) than thyroid (11.3%) (P = 0.111). Needle size did not affect adequacy, but the number of passes was a significant predictor (odds ratio: 0.068, 95% confidence interval: 0.008-0.570, P = 0.013).
Conclusion: The study highlights the importance of the number of passes during the procedure, with a higher number of passes associated with decreased odds of obtaining an adequate sample. The needle size does not significantly impact the various variables assessed.
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