Investigations on the Antimicrobial Activity of V2–xSb2xO5–δ Compound Systems Against the Gram-Positive, Gram-Negative Bacteria, Penicillium, and Aspergillus niger Fungi

Abstract

Recent innovations in antimicrobial coatings for surgical tools and implants utilize engineered multi-cation oxides combined with nanofibers, nanotubes, and nanosheets, which generate reactive oxygen species to effectively reduce infection risk. This research provides an in-depth examination of lattice dynamics through Raman spectroscopy and ten Raman bands observed from the study indicate the vibrational modes of the orthorhombic structure of V_2–xSb_2xO_5–δ (Sb–V–O, 0.05 ≤ x ≤ 0.08) compounds with the polycrystalline nature of the powder ceramics. The study also assesses the antibacterial properties of Sb–V–O compounds against both human pathogenic gram-positive and gram-negative bacteria. Additionally, the antifungal effectiveness of these compounds is tested against Penicillium spp. and Aspergillus niger. Streptomycin and metronidazole are utilized as positive controls, while dimethyl sulfoxide is used as a negative control. The results highlight the diverse characteristics of the compounds, illustrating their broad-spectrum antimicrobial capabilities and their potential applications in various biomedical and industrial fields.