Prognostic Value of Intravascular Optical Coherence Tomography in Patients With Coronary Heart Disease Undergoing Percutaneous Coronary Intervention.

IF 2.3

Journal of biophotonics Pub Date : 2025-08-23 DOI:10.1002/jbio.202500184

Zhengya Fang, Suwen Zhu, Shaodong Zhang, Yingchun Liu, Yueyun Shen, Ye Zhang

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Abstract

Objective: We aimed to ascertain the predictive value of intravascular optical coherence tomography (OCT) in the prognosis of coronary heart disease (CHD) patients undergoing percutaneous coronary intervention (PCI).

Methods: Independent factors affecting major adverse cardiac events (MACE) and predictive efficacy of OCT parameters on MACE in CHD patients were analyzed.

Results: Advanced age and large lipid arc degree were risk factors for MACE occurrence (OR > 1, p < 0.05), while thick fibrous cap thickness and high left ventricular ejection fraction were protective (OR < 1, p < 0.05). Fibrous cap thickness predicted MACE (AUC 0.765, 95% CI 0.690 ~ 0.840, cut-off 92 μm); lipid arc degree did as well (AUC 0.885, 95% CI 0.817 ~ 0.952, cut-off 214.5°).

Conclusion: OCT supports interventional treatment in CHD patients, with fibrous cap thickness and lipid arc degree demonstrating some prognostic predictive value post-PCI.

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血管内光学相干断层扫描对冠心病患者经皮冠状动脉介入治疗的预后价值。

目的：探讨血管内光学相干断层扫描（OCT）对冠心病（CHD）患者经皮冠状动脉介入治疗（PCI）预后的预测价值。方法：分析影响冠心病患者主要心脏不良事件（MACE）的独立因素及OCT参数对MACE的预测作用。结果：高龄和较大的脂质弧度是发生MACE的危险因素（OR >, 1, p）。结论：OCT支持冠心病患者介入治疗，纤维帽厚度和脂质弧度在pci后具有一定的预后预测价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of biophotonics

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