Volumetric variations in the buccal fat pad, parapharyngeal adipose corpus, and orbital fat according to sex, age, and body mass index: an MRI study with segmentation.
A Fernandez, L-D Rivière, T Canceill, A Dubuc, G Fournier, F Savall, G de Bonnecaze
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引用次数: 0
Abstract
The buccal fat pad (BFP), pharyngeal adipose corpus (PAC), and orbital fat are deep fatty compartments of the face that are often considered as non-mobilized fat and are excluded from lipid metabolism. There is considerable clinical inter-individual variability in BFP volume. The PAC volume, which is influenced by weight gain, may be involved in obstructive sleep apnoea syndrome. The aim of this study was to (1) establish well-defined segmentation protocols for the deep fat compartments of the midface; (2) study the volumetric variation in the deep fat compartments of the face according to body mass index (BMI), age, and sex; and (3) compare the behaviours of these fat volumes with each other. Volumes were measured using 3D segmentation tools (3D Slicer). This multicentre study investigated 63 MRI obtained retrospectively. Sex, age, and BMI data were collected from the patient files. The facial deep fat volumes were found to be positively correlated with age and BMI, to varying degrees but in the same direction. No difference in volumes was found between males and females: BFP, P = 0.70; PAC, P = 0.19; orbital fat, P = 0.11. A patient's age and BMI may provide clues as to the volumes of the deep fat compartments. These findings provide a strong foundation for further studies.
颊脂肪垫(BFP)、咽脂肪体(PAC)和眶脂肪是面部深层脂肪区,通常被认为是非动员脂肪,被排除在脂质代谢之外。BFP体积有相当大的临床个体差异。PAC体积受体重增加的影响,可能与阻塞性睡眠呼吸暂停综合征有关。本研究的目的是:(1)为面部中部的深层脂肪区建立明确的分割方案;(2)研究面部深层脂肪区体积随体重指数(BMI)、年龄和性别的变化;(3)比较这些脂肪体积的行为。使用3D分割工具(3D切片器)测量体积。本多中心研究回顾性调查了63例MRI。从患者档案中收集性别、年龄和BMI数据。研究发现,面部深层脂肪量与年龄和BMI呈正相关,虽然程度不同,但方向相同。男性和女性在体积上没有差异:BFP, P = 0.70;Pac, p = 0.19;轨道脂肪,P = 0.11。病人的年龄和身体质量指数可以提供深部脂肪区室体积的线索。这些发现为进一步的研究提供了坚实的基础。