[Clinical efficacy of demineralized dentin matrix particles in immediate implantation for bone defects in posterior region: a 1 to 5-year follow-up study].

Hao Wu, Ning Cao, Liangwei Cao, Fei Yu, Xu Zhang, Shibo Wei, Hongwu Wei, Shuigen Guo
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引用次数: 0

Abstract

Objectives: This study aims to evaluate the short- to medium-term clinical efficacy of demineralized dentin matrix (DDM) particles applied during the immediate implantation of alveolar bone defects in the posterior region.

Methods: A total of 76 patients with 110 simple taper retentive implants were included in the conducted study and divided into Groups A and B in accordance with the bone grafting materials. Cone beam computed tomography and panoramic radiographs were taken immediately after implant surgery, immediate crown repair, and final follow-up time. The average follow-up time for Groups A and B was recorded. The primary observed clinical indicators were overall survival rate of the implant, bone resorption of the mesial and distal margins of the implant, buccal bone width resorption at the platform level and 1 mm below the platform, and bone height of the implant. Implant complication was a secondary observed clinical indicator.

Results: During the 1-to-5-year follow-up observation period, the mean follow-up of Group A was 38.2 months while that of Group B was 39.9 months. In Group A, two implants failed, one of which fractured, and implant overall survival rate was 96.4%. Four implants failed in Group B due to peri-implantitis, and implant overall survival rate was 92.6%. No statistically significant difference in implant overall survival rate was found between the two groups (P>0.05). In Group A, the average bone resorption in the mesial and distal margins of the implants was (1.011±2.047) mm and (0.841±2.183) mm, respectively. In Group B, the average bone resorption of the mesial and distal margins of the implants was (1.546±1.778) mm and (1.431±1.909) mm, respectively. No statistically significant difference was noted between the two groups (P>0.05). In Group A, buccal bone width resorption at the platform level and 1 mm below the platform of the implant was (0.782±2.084) mm and (0.681±2.307) mm, respectively. In Group B, buccal bone width resorption at the platform level and 1 mm below the platform of implant was (1.071±1.474) mm and (0.949±1.909) mm, respectively. No statistically significant difference was found between the two groups (P>0.05). In Group A, the buccal bone height of resorption of the implant was (1.044±2.214) mm. In Group B, the buccal bone height of resorption of the implant was (1.075±1.456) mm. No statistically significant difference in bone height was observed between the two groups (P>0.05).

Conclusions: During the 1-to-5-year follow-up observation period, DDM particles can effectively increase the height and width of alveolar bone, and they can achieve the same effect of maintaining alveolar bone contour and bone augmentation compared with deproteinized inorganic calf bone. DDM particles can be used as a potential new bone grafting material for the treatment of bone defects in clinical practice.

【脱矿牙本质基质颗粒即刻种植修复后牙区骨缺损的临床疗效:1 ~ 5年随访研究】。
目的:评价脱矿牙本质基质(DDM)颗粒用于后牙槽骨缺损即刻种植的中短期临床疗效。方法:选取76例简易锥形固定种植体110例,根据植骨材料分为A组和B组。锥形束计算机断层扫描和全景x线片在种植手术后立即进行,立即修复冠,最后随访时间。记录A组和B组的平均随访时间。主要观察临床指标为种植体总体存活率、种植体近缘和远缘骨吸收、平台水平及平台下方1mm颊骨宽度吸收、种植体骨高度。种植体并发症是观察到的次要临床指标。结果:1 ~ 5年随访观察期内,A组平均随访38.2个月,B组平均随访39.9个月。A组2例种植体失败,1例骨折,种植体总生存率为96.4%。B组4例种植体因种植体周围炎失败,种植体总生存率为92.6%。两组种植体总存活率比较,差异无统计学意义(P < 0.05)。A组种植体近缘和远缘骨吸收平均分别为(1.011±2.047)mm和(0.841±2.183)mm。B组种植体近缘和远缘平均骨吸收率分别为(1.546±1.778)mm和(1.431±1.909)mm。两组间比较差异无统计学意义(P < 0.05)。A组种植体平台处和平台下方1mm处颊骨宽度吸收分别为(0.782±2.084)mm和(0.681±2.307)mm。B组种植体平台水平和种植体平台以下1mm颊骨宽度吸收分别为(1.071±1.474)mm和(0.949±1.909)mm。两组间比较差异无统计学意义(P < 0.05)。A组种植体吸收颊骨高度为(1.044±2.214)mm, B组种植体吸收颊骨高度为(1.075±1.456)mm,两组骨高度比较差异无统计学意义(P < 0.05)。结论:在1 ~ 5年的随访观察期内,DDM颗粒可有效增加牙槽骨的高度和宽度,与脱蛋白无机小牛骨相比,可达到维持牙槽骨轮廓和增骨的相同效果。DDM颗粒可作为一种潜在的新型骨移植材料用于临床治疗骨缺损。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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