{"title":"Dependence, abuse, and psychosocial characteristics of patients transported to the emergency department due to overdose of over-the-counter drugs.","authors":"Saeko Kohara, Michiko Takai, Ryoko Kyan, Kenji Yamamoto, Hidehito Miyazaki, Masafumi Yoshimura, Yoshito Kamijo","doi":"10.1002/pcn5.70181","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study examined the conditions of drug abuse and dependence as well as the psychosocial characteristics of patients transported to an emergency department for over-the-counter (OTC) drug overdose.</p><p><strong>Methods: </strong>Participants were patients who presented to the emergency department due to an overdose of OTC drugs. Patients were evaluated using the Drug Abuse Screening Test-20 (DAST-20), Mini International Neuropsychiatric Interview (MINI), and an original questionnaire.</p><p><strong>Results: </strong>The study included 52 patients from four emergency medical facilities (20 males and 32 females) with a mean age of 23.6 years (standard deviation = 10.1). The DAST-20 indicated that 17 patients (32.7%) experienced moderate or severe drug abuse. The average score for suicide risk on the MINI was 23.7 (median: 27). The severity of OTC drug abuse and dependence significantly correlated with drug overdose history (<i>r</i> = 0.44, <i>p</i> < 0.01), OTC drug type (antitussives and expectorants) (<i>r</i> = 0.36, <i>p</i> < 0.01), experience with OTC drug abuse (<i>r</i> = 0.53, <i>p</i> < 0.01), overdose purpose (relief of distress) (<i>r</i> = 0.41, <i>p</i> < 0.01), and overdose purpose (suicide) (<i>r</i> = -0.52, <i>p</i> < 0.01). The severity of drug abuse and dependence was best predicted by the combination of experience with OTC drug abuse, an advisor, and suicidal purpose (<i>R</i> <sup>2</sup> = 0.53, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>It is crucial to investigate patient experiences with OTC drug abuse and their motivations and backgrounds for overdosing. Support for abuse and dependence should be provided in the early stages of treatment.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"4 3","pages":"e70181"},"PeriodicalIF":0.9000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397076/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PCN reports : psychiatry and clinical neurosciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/pcn5.70181","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: This study examined the conditions of drug abuse and dependence as well as the psychosocial characteristics of patients transported to an emergency department for over-the-counter (OTC) drug overdose.
Methods: Participants were patients who presented to the emergency department due to an overdose of OTC drugs. Patients were evaluated using the Drug Abuse Screening Test-20 (DAST-20), Mini International Neuropsychiatric Interview (MINI), and an original questionnaire.
Results: The study included 52 patients from four emergency medical facilities (20 males and 32 females) with a mean age of 23.6 years (standard deviation = 10.1). The DAST-20 indicated that 17 patients (32.7%) experienced moderate or severe drug abuse. The average score for suicide risk on the MINI was 23.7 (median: 27). The severity of OTC drug abuse and dependence significantly correlated with drug overdose history (r = 0.44, p < 0.01), OTC drug type (antitussives and expectorants) (r = 0.36, p < 0.01), experience with OTC drug abuse (r = 0.53, p < 0.01), overdose purpose (relief of distress) (r = 0.41, p < 0.01), and overdose purpose (suicide) (r = -0.52, p < 0.01). The severity of drug abuse and dependence was best predicted by the combination of experience with OTC drug abuse, an advisor, and suicidal purpose (R2 = 0.53, p < 0.001).
Conclusion: It is crucial to investigate patient experiences with OTC drug abuse and their motivations and backgrounds for overdosing. Support for abuse and dependence should be provided in the early stages of treatment.
目的:本研究考察了因非处方(OTC)药物过量而被送往急诊室的患者的药物滥用和依赖状况以及心理社会特征。方法:研究对象为因过量服用非处方药而就诊于急诊科的患者。采用药物滥用筛选测试20 (DAST-20)、Mini国际神经精神病学访谈(Mini)和原始问卷对患者进行评估。结果:本研究纳入了来自4家急救医疗机构的52例患者(男性20例,女性32例),平均年龄23.6岁(标准差= 10.1)。DAST-20显示有17例(32.7%)患者存在中度或重度药物滥用。MINI的自杀风险平均得分为23.7分(中位数:27分)。非处方药物滥用和依赖严重程度与药物过量史显著相关(r = 0.44, p r = 0.36, p r = 0.53, p r = 0.41, p r = -0.52, p r 2 = 0.53, p)结论:了解患者的非处方药物滥用经历及其过量用药动机和背景至关重要。应在治疗的早期阶段提供对滥用和依赖的支持。