Chorion Membrane and Concentrated Growth Factor Membrane in Treating Bilateral Miller's Class I and II Gingival Recessions in Maxillary Premolars - a Clinical Study.

Kowsalya Nallathambi, Ramnath Elangovan, Dinesh C Maganti, Anitha Maganti, Dona Soman, Niranjan Diwekar
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Abstract

Background: Periodontitis causes many clinical presentations, one of which is gingival recession, which leads to root exposure, hypersensitivity and esthetic issues. One of the most accepted surgical procedures of root coverage is the coronally advanced flap (CAF) technique. Newer regenerative modalities such as placental-derived chorion membranes and autologous concentrated growth factor (CGF) membranes have a higher capacity to heal because of the bioactive nature of these membranes. Material and method: A randomized controlled clinical trial study was carried out on 10 patients with bilateral gingival recession in maxillary premolars. They happened to receive CAF with chorion membrane on one side (Group A) and CGF membrane on the other side (Group B). Such clinical parameters as probing depth (PD), clinical attachment level (CAL), recession height (RH), recession width (RW) and width of keratinized tissue (WKT) were measured at baseline and after three months of follow-up. Paired and unpaired t-tests were undertaken through IBM SPSS 23.0. Results: In both groups, all clinical parameters improved statistically significant after the surgery (p < 0.05). Group A root coverage mean was 89 percent and Group B 82 percent. The postoperative values of PD, CAL, RH, RW and WKT did not differ statistically between the two groups (p < 0.05), but Group A had slightly superior results. Conclusions: Human chorion membrane and concentrated growth factor membrane being used with CAF lead to effective root coverage and clinical improvement, which is considered significant in Miller Class I and II gingival recessions. Both membranes are effective, but the chorion membrane might provide slightly better clinical results. Longitudinal research involving bigger samples should be done.

绒毛膜和浓缩生长因子膜治疗双侧上颌前磨牙米勒氏ⅰ、ⅱ类牙龈萎缩的临床研究。
背景:牙周炎引起许多临床表现,其中之一是牙龈萎缩,导致牙根暴露,过敏和审美问题。冠状推进皮瓣(CAF)技术是最被接受的根覆盖手术之一。较新的再生方式,如胎盘来源的绒毛膜和自体浓缩生长因子(CGF)膜,由于这些膜的生物活性性质,具有更高的愈合能力。材料与方法:对10例上颌前磨牙双侧牙龈退缩患者进行随机对照临床试验研究。它们碰巧接受了一侧有绒毛膜(A组)和另一侧有CGF膜(B组)的CAF。在基线和随访3个月后测量探查深度(PD)、临床附着水平(CAL)、退退高度(RH)、退退宽度(RW)和角化组织宽度(WKT)等临床参数。通过IBM SPSS 23.0进行配对和非配对t检验。结果:两组患者术后各项临床指标改善均有统计学意义(p < 0.05)。A组的平均根盖度为89%,B组为82%。两组术后PD、CAL、RH、RW、WKT值比较,差异无统计学意义(p < 0.05),但A组结果略优于A组。结论:人绒毛膜和浓缩生长因子膜与CAF联合使用可有效覆盖牙根,改善临床,对Miller I类和II类牙龈衰退具有重要意义。两种膜都是有效的,但绒毛膜可能提供稍微更好的临床结果。应该进行涉及更大样本的纵向研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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