Endobiliary Radiofrequency Ablation for Hepato-Biliary Diseases: A Narrative Review.

IF 3 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Tawfik Khoury, Wisam Sbeit, Andrea Lisotti, Bertrand Napoléon
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引用次数: 0

Abstract

Background/objectives: Malignant biliary diseases still represent a therapeutic challenge given its poor prognosis, and limited response to the available curative treatments. Recently, endobiliary radiofrequency ablation (RFA) has been increasingly reported as an adjunct therapeutic option for biliary diseases, especially malignant biliary obstruction (MBO), due to potentially improving survival and stent patency.

Methods: Herein, we provide a comprehensive review article discussing the indication, procedural details, safety, and comparative efficacy of endobiliary RFA to aid in providing an in-depth understanding of the clinical indications and future implications of this specific option.

Results: Overall, endobiliary RFA is technically feasible, being associated with a high safety profile, significantly improving biliary stent patency, and having a potential benefit in extending the survival of patients with MBO who were treated with endobiliary RFA combined with biliary stenting vs. stenting alone. Moreover, it has a promising role in the treatment of intraductal extension of ampullary tumors.

Conclusions: Endobiliary RFA had a beneficial therapeutic effect in biliary strictures, with potential impact on patients outcome and survival.

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胆道内射频消融术治疗肝胆疾病:综述
背景/目的:恶性胆道疾病由于其预后不良,对现有治疗方法的反应有限,仍然是一个治疗挑战。最近,胆道内射频消融(RFA)越来越多地被报道为胆道疾病,特别是恶性胆道梗阻(MBO)的辅助治疗选择,因为它可能提高生存率和支架通畅性。方法:在此,我们提供了一篇全面的综述文章,讨论了肠内射频消融术的适应症、手术细节、安全性和比较疗效,以帮助深入了解这种特定选择的临床适应症和未来的意义。结果:总的来说,胆道内RFA在技术上是可行的,具有很高的安全性,显著提高了胆道支架的通畅性,并且在延长MBO患者的生存期方面具有潜在的益处,这些患者接受了胆道内RFA联合胆道支架置入治疗,而不是单独支架置入。此外,它在壶腹肿瘤导管内延伸的治疗中也有很好的应用前景。结论:胆道内射频消融术对胆道狭窄有良好的治疗效果,对患者的预后和生存有潜在的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
0
审稿时长
6 weeks
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