General Practitioner Coordinated Multidisciplinary Care Improves Long-Term Survival following Stroke with Variation by Impairment.

IF 4 3区 医学 Q2 CLINICAL NEUROLOGY
Nadine E Andrew, David Ung, Monique F Kilkenny, Muideen T Olaiya, Lachlan L Dalli, Leonid Churilov, Taya Collyer, David A Snowdon, Joosup Kim, Velandai Srikanth, Dominique A Cadilhac, Vijaya Sundararajan, Amanda G Thrift, Mark R Nelson, Natasha A Lannin
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引用次数: 0

Abstract

Background: Australian Medicare funded policies to support General Practtitioners (GPs) to coordinate multidisciplinary care (MDC) with other healthcare providers have potential to benefit survivors of stroke/transient ischaemic attack (TIA). However, the effectiveness of these policies is unknown. We aimed to determine the population effect of such policies in improving long-term outcomes following stroke/TIA, by impairment grouping.

Methods: Target trial emulation using observational data within a cohort of community-dwelling adults with stroke/TIA from the Australian Stroke Clinical Registry (January 2012-December 2016, 42 hospitals). Person-level Medicare, pharmacy, aged care, death, and hospital records were linked. The exposure was ≥1 Medicare GP-MDC claim 6-18 months post-stroke. Outcomes were survival and hospitalisations at 19-30 months. Impairment group (minimal, moderate, severe) was classified by latent class analysis of EQ-5D-3L questionnaire data obtained 90-180 days post-stroke. Analysis comprised multivariable, multilevel survival analysis with inverse probability treatment weights (42 covariates).

Results: The cohort comprised 7,255 people with stroke (42% female, median age 71 years, 24% TIA, impairment: 39% minimal, 32% moderate, 29% severe, 29% had a MDC claim). More claims occurred with each increasing level of impairment group: minimal 22%; moderate 30%; severe 37%. Twelve-month mortality was reduced in those with ≥1 MDC claim (compared to those without) in the minimal (adjusted hazard ratio [aHR]: 0.50, 95% CI: 0.27, 0.91) and severe (aHR: 0.65, 95% CI: 0.46, 0.91) impairment groups, but not in the moderate group (aHR: 1.31, 95% CI: 0.86, 1.99). Compared to those without a claim, hospital presentations were greater in the minimal (aHR: 1.30, 95% CI: 1.06, 1.59) and moderate impairment groups (aHR: 1.40, 95% CI: 1.23, 1.60) but not the severe group (aHR: 1.05, 95% CI: 0.85, 1.30).

Conclusions: Government policy incentives for GP-coordinated MDC were effective at the population level at improving long-term survival outcomes, in those with minimal and severe impairments.

全科医生协调的多学科护理可提高脑卒中患者的长期生存率。
背景:澳大利亚医疗保险资助政策支持初级保健医生(全科医生)与其他医疗保健提供者协调多学科护理(MDC)有可能使中风/短暂性脑缺血发作(TIA)的幸存者受益。然而,这些政策的有效性是未知的。我们的目的是通过损伤分组来确定这些政策在改善卒中/TIA后长期预后方面的人群效应。方法:目标试验模拟使用来自澳大利亚卒中临床登记处(2012年1月- 2015年6月,42家医院)的卒中/TIA社区居住成人队列的观察数据。个人层面的医疗保险、药房、老年护理、死亡和医院记录被联系起来。卒中后6-18个月,暴露率≥1。结果是19-30个月的生存和住院。根据脑卒中后90-180天获得的EQ-5D-3L问卷数据进行潜在分类分析,将损伤组分为轻度、中度、重度。分析包括采用反概率处理权(42个协变量)的多变量、多水平生存分析。结果:该队列包括7255名卒中患者(42%为女性,中位年龄71岁,24%为TIA,损伤:39%轻度,32%中度,29%重度,29%有MDC声称)。随着损伤程度的增加,更多的索赔发生:最低22%;温和的30%;严重的37%。在最小(调整后的危险比(aHR):0.50, 95% CI:0.27, 0.91)和严重(aHR:0.65, 95% CI:0.46, 0.91)损害组中,MDC索赔≥1例的患者(与无MDC索赔者相比)12个月死亡率降低,但在中度损害组中没有(aHR:1.31, 95% CI:0.86, 1.99)。与没有索赔的患者相比,轻度损伤组(aHR:1.30, 95%CI:1.06, 1.59)和中度损伤组(aHR:1.40, 95%CI:1.23, 1.60)的住院率更高,而重度损伤组(aHR:1.05, 95%CI:0.85, 1.30)的住院率更高。结论:在人群水平上,政府对与gdp协调的MDC的政策激励在改善轻度和重度损伤患者的长期生存结果方面是有效的。
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来源期刊
Neuroepidemiology
Neuroepidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
9.90
自引率
1.80%
发文量
49
审稿时长
6-12 weeks
期刊介绍: ''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.
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