{"title":"Obesity And The Spleen.","authors":"Sanjay Kalra, Suneet Kumar Vermaz, Nitin Kapoor","doi":"10.47391/JPMA.25-63","DOIUrl":null,"url":null,"abstract":"<p><p>This review describes the relationship of splenomegaly, or \"splenic obesity\", with metabolic syndrome, obesity and metabolic - associated steatohepatic disease (MAFLD), based on animal and human studies. The spleen is enlarged in obesity. It may play a protective role against obesity-associated inflammation and complications. This protection may be lost after splenomegaly. Persons with splenic disease must be evaluated for obesity, and vice versa and counselled to avoid injury to the organ.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1298-1300"},"PeriodicalIF":0.8000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Pakistan Medical Association","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.47391/JPMA.25-63","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
This review describes the relationship of splenomegaly, or "splenic obesity", with metabolic syndrome, obesity and metabolic - associated steatohepatic disease (MAFLD), based on animal and human studies. The spleen is enlarged in obesity. It may play a protective role against obesity-associated inflammation and complications. This protection may be lost after splenomegaly. Persons with splenic disease must be evaluated for obesity, and vice versa and counselled to avoid injury to the organ.
期刊介绍:
Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.