Risk Factor Analysis of Gestational Diabetes Mellitus Across Urban India: Findings from the Pregnancy Study Group.

IF 0.6 Q4 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynecology of India Pub Date : 2025-08-01 Epub Date: 2025-06-28 DOI:10.1007/s13224-025-02178-6

Rutul Gokalani, Ami Sanghvi, Shefali Karlhanis, Prashanth Sankar, Dharmendra Panchal, Ashish Dengra, Bharat Saboo, Sunil Kota, Mahira Saiyed, Banshi Saboo, Shalini Jaggi, Rajeev Chawla

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引用次数: 0

Abstract

Background: GDM is an intermediate phase in a woman's life that certainly poses a high risk of type 2 diabetes. Maternal health affects the health of offspring, a precursor of the vicious cycle of diabetes that continues through generations. Knowing the causative factors of GDM is important to breaking this cycle.

Objective: To study the risk factors of GDM in Indian women.

Method: The observational study database records from 2022 to 2023 from 11 different centres across India. We included pregnant women diagnosed with GDM with any OGTT criteria and excluded women with pre-existing diabetes.

Results: A total of 431 women with GDM were included in the study. 166 women were diagnosed with GDM in the 3rd trimester, followed by 235 women in the 2nd trimester, and 30 women in the 1st trimester of pregnancy. Those detected with GDM during the 1st trimester had a BMI of 27.9 kg/m2, followed by 28.3 and 29.3 kg/m2 in 3rd trimester. Multigravida showed a positive correlation with a family history of T2D (0.04), previous history of GDM (p-value < 0.001), history of stillbirth (p-value < 0.001) and hypertension (p-value 0.03).

Conclusion: Pre-pregnancy BMI and women's age at family planning are two important risk factors for the prevention of gestational diabetes.

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印度城市妊娠期糖尿病的危险因素分析：来自妊娠研究组的发现。

背景：GDM是女性生命中的一个中间阶段，当然会导致2型糖尿病的高风险。产妇健康影响后代的健康，是糖尿病恶性循环的先兆，这种恶性循环会代代相传。了解GDM的致病因素对于打破这种循环非常重要。目的：探讨印度女性GDM的危险因素。方法：观察性研究数据库记录了印度11个不同中心2022年至2023年的数据。我们纳入了诊断为GDM并符合任何OGTT标准的孕妇，排除了已有糖尿病的妇女。结果：共有431名GDM女性纳入研究。166名妇女在妊娠晚期被诊断为GDM， 235名妇女在妊娠晚期被诊断为GDM， 30名妇女在妊娠早期被诊断为GDM。妊娠早期发现GDM的孕妇BMI为27.9 kg/m2，妊娠晚期BMI分别为28.3和29.3 kg/m2。多胎妊娠与T2D家族史（0.04）、既往GDM史（p-value p-value 0.03）呈正相关。结论：孕前BMI和计划生育年龄是预防妊娠期糖尿病的重要危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obstetrics and Gynecology of India OBSTETRICS & GYNECOLOGY-

CiteScore

1.30

自引率

0.00%

发文量

124

期刊介绍： Journal of Obstetrics and Gynecology of India (JOGI) is the official journal of the Federation of Obstetrics and Gynecology Societies of India (FOGSI). This is a peer- reviewed journal and features articles pertaining to the field of obstetrics and gynecology. The Journal is published six times a year on a bimonthly basis. Articles contributed by clinicians involved in patient care and research, and basic science researchers are considered. It publishes clinical and basic research of all aspects of obstetrics and gynecology, community obstetrics and family welfare and subspecialty subjects including gynecological endoscopy, infertility, oncology and ultrasonography, provided they have scientific merit and represent an important advance in knowledge. The journal believes in diversity and welcomes and encourages relevant contributions from world over. The types of articles published are: · Original Article· Case Report · Instrumentation and Techniques · Short Commentary · Correspondence (Letter to the Editor) · Pictorial Essay