Sofia Germano Travieso, Gabriela Ueta Ortiz, Gabriela Ferreira Abud, Marina Mello Villalba, Gizela Pedroso Junqueira, Matheus Machado Gomes, Julio Sergio Marchini, Ellen Cristini Freitas
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引用次数: 0
Abstract
Introduction: The aging global population demands strategies to mitigate inflammation and anabolic resistance impacting older adults' quality of life. This randomized controlled trial examined the effects of multicomponent training on obese older women to enhance muscle health and functionality.
Objectives: To assess the effects of a 12-week multicomponent training program on physical and functional capacities, body composition, metabolic health, and whole body muscle quality.
Methods: Twenty-six older women (body mass index: >30 kg/m2) were randomized into an exercise (n = 13) or control group (n = 13). Exercise group participated in 12 weeks of supervised multicomponent training. Outcomes assessed pre- and postintervention including functional and physical capacities, body composition, waist circumference, lower limb muscle ultrasound, lipid profile, blood glucose, glucose tolerance, inflammatory cytokines, and type III procollagen peptide protein. Assessments were conducted blind to group allocation. Data were analyzed using R software.
Results: Exercise group showed significant reductions in body fat percentage (Hedges' g: -0.14) and enhanced functional performance (sit-to-stand test: Hedges' g: 1.21). Improvements in cardiometabolic health and inflammatory profiles were observed, reducing morbidity risk. Correlations between inflammatory markers, body composition, and functional outcomes suggested a nonlinear cytokine response.
Conclusion: Multicomponent training effectively improved body composition and functional capacity in obese older women, with potential benefits for inflammatory and metabolic health.
Significance: These results underscore the importance of integrating exercise with dietary strategies to optimize outcomes.
期刊介绍：
The Journal of Aging and Physical Activity (JAPA) is a multidisciplinary journal that publishes peer-reviewed original research reports, scholarly reviews, and professional-application articles on the relationship between physical activity and the aging process. The journal encourages the submission of articles that can contribute to an understanding of (a) the impact of physical activity on physiological, psychological, and social aspects of older adults and (b) the effect of advancing age or the aging process on physical activity among older adults.
In addition to publishing research reports and reviews, JAPA publishes articles that examine the development, implementation, and evaluation of physical activity programs among older adults. Articles from the biological, behavioral, and social sciences, as well as from fields such as medicine, clinical psychology, physical and recreational therapy, health, physical education, and recreation, are appropriate for the journal. Studies using animal models do not fit within our mission statement and should be submitted elsewhere.
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