Early detection of acute mandibular osteomyelitis using computed tomography texture analysis

IF 1.9 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-07-23 DOI:10.1016/j.oooo.2025.07.008

Hirotaka Muraoka DDS, PhD, Takashi Kaneda DDS, PhD, Kotaro Ito DDS, PhD, Kohei Otsuka DDS, PhD, Satoshi Tokunaga DDS, PhD

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引用次数: 0

Abstract

Objectives

Early detection of acute suppurative osteomyelitis is difficult in clinical practice. The aim of this study was to evaluate the usefulness of computed tomography (CT) texture analysis in diagnosing acute mandibular osteomyelitis.

Materials and Methods

Seventeen patients who complained of severe mandibular pain and underwent CT examinations between July 2018 and September 2023 were included in the study. MaZda ver.3.3 software was used to extract 279 texture features from region of interests (ROIs) on CT images of patients with osteomyelitis (n = 17) and controls (contralateral sides) (n = 17). The acute osteomyelitis sites and controls were compared for each feature, and the 6 features that differed most significantly between groups were selected using Fisher's coefficient. The groups were compared using the Wilcoxon signed-rank test or paired t-test. Significance was set at P < 0.05. Receiver operating characteristic curves were used to evaluate the ability of the CT texture features to detect acute osteomyelitis.

Results

Significant differences in all 6 features were observed between the acute osteomyelitis and controls (P < 0.001). The sensitivity, specificity, accuracy, and area under the curve for detecting acute osteomyelitis were 0.94–1.0, 0.94–1.0, 0.97–1.0, and 0.96–1.0, respectively.

Conclusions

CT texture analysis may be useful in the early detection of acute mandibular osteomyelitis.

查看原文本刊更多论文

急性下颌骨骨髓炎的计算机断层结构分析。

目的：急性化脓性骨髓炎的早期诊断是临床实践中的难点。本研究的目的是评估计算机断层扫描（CT）纹理分析在诊断急性下颌骨髓炎中的有用性。材料和方法：2018年7月至2023年9月期间，17例主诉严重下颌疼痛并接受CT检查的患者被纳入研究。采用MaZda ver.3.3软件对骨髓炎患者（n = 17）和对照组（n = 17） CT图像的感兴趣区域（roi）提取279个纹理特征。比较急性骨髓炎部位与对照组各特征，采用Fisher系数法选择组间差异最大的6个特征。各组间比较采用Wilcoxon符号秩检验或配对t检验。P < 0.05为显著性。采用受试者工作特征曲线评价CT纹理特征检测急性骨髓炎的能力。结果：急性骨髓炎患者与对照组6项指标均有显著性差异（P < 0.001）。检测急性骨髓炎的敏感性、特异性、准确性和曲线下面积分别为0.94-1.0、0.94-1.0、0.97-1.0和0.96-1.0。结论：CT结构分析可用于早期发现急性下颌骨髓炎。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.