Subcortical bone marrow and deep marrow differences: A comparison in a series of 5 cases.

Abstract

This manuscript documents examples of bone marrow cores where subcortical spaces are significantly different in comparison with deep core spaces. The differences include significantly higher or lower cellularity in addition to discrepant involvement by malignant processes. While this phenomenon is generally familiar to practicing pathologists, it is not adequately illustrated in the medical literature. Publication of such illustrated examples may help generate more interest in this phenomenon as well as emphasise the constant need for adequate marrow specimens to avoid diagnostic pitfalls.