Lorlatinib Achieved Rapid CNS Response in an 81-Year-Old NSCLC Patient With Performance Status Deterioration.

IF 0.8 Q4 RESPIRATORY SYSTEM

Respirology Case Reports Pub Date : 2025-08-21 eCollection Date: 2025-08-01 DOI:10.1002/rcr2.70320

Akina Nigi, Keisuke Iwamoto, Hidetoshi Itani, Shigeto Kondou

引用次数: 0

Abstract

Lorlatinib may offer rapid CNS symptom and imaging improvement after alectinib failure, even in elderly ALK-positive NSCLC patients with declining performance status.

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Lorlatinib在81岁表现恶化的NSCLC患者中实现了快速中枢神经系统反应。

Lorlatinib可以在alectiinib失效后快速改善中枢神经系统症状和影像学，即使是在表现下降的老年alk阳性NSCLC患者中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Respirology Case Reports RESPIRATORY SYSTEM-

CiteScore

1.40

自引率

0.00%

发文量

178

审稿时长

8 weeks

期刊介绍： Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.