An unusual presentation of cutaneous sarcoidosis induced by Koebner's phenomenon.

IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL
Oxford Medical Case Reports Pub Date : 2025-08-25 eCollection Date: 2025-08-01 DOI:10.1093/omcr/omaf147
Maryam Ghaleb, Ouiame El Jouari, Salim Gallouj
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引用次数: 0

Abstract

We report an unusual case of cutaneous sarcoidosis presenting as papulonodular lesions strictly localized to the nasal bridge and medial canthus-corresponding to areas of pressure from eyeglass frames. This rare distribution suggests the involvement of Koebner's phenomenon, a form of reactive isomorphism rarely reported in sarcoidosis. The cutaneous lesions, present for four years, led to dermatological evaluation and subsequent histopathological confirmation of sarcoidosis. Biological and radiological investigations further revealed pulmonary involvement, establishing the diagnosis of systemic sarcoidosis. The patient was treated with hydroxychloroquine and intra-lesional corticosteroids, showing marked improvement after three months and no recurrence at six months. This case underscores the importance of recognizing atypical presentations of cutaneous sarcoidosis, which may serve as an early clinical gateway to the diagnosis of systemic disease.

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由Koebner现象引起的皮肤结节病的不寻常表现。
我们报告一个不寻常的皮肤结节病的情况下,表现为丘疹样病变严格定位于鼻梁和内侧眦-对应的区域压力从眼镜框架。这种罕见的分布提示涉及Koebner现象,这是一种在结节病中很少报道的反应性同构现象。皮肤病变,存在四年,导致皮肤病学评估和随后的组织病理学结节病的确认。生物学和放射学检查进一步显示肺部受累,建立全身性结节病的诊断。患者接受羟氯喹和病灶内皮质类固醇治疗,3个月后病情明显好转,6个月无复发。本病例强调了识别皮肤结节病的非典型表现的重要性,这可能是诊断全身性疾病的早期临床途径。
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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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