{"title":"Demographics of plateletpheresis donors and session profile in a teaching institute of Punjab.","authors":"Harnoor Singh Bhardwaj, Amarjit Kaur, Rajesh Kumar, Sonia Gupta","doi":"10.4103/ajts.ajts_39_21","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Over decades, increased demand of platelet transfusions for patients with various conditions led to accelerated use of technologically advanced plateletpheresis.</p><p><strong>Aims: </strong>Study the demographics of plateletpheresis donor and plateletpheresis session profile.</p><p><strong>Setting and design: </strong>Prospective, cross-sectional, open label study.</p><p><strong>Materials and methods: </strong>Plateletpheresis performed on Trima Accel (TA) and mechanical circulatory support (MCS) + during 2017-2018 on donors selected according to the guidelines.</p><p><strong>Statistical analysis: </strong>SPSS (version 17) for windows statistical package.</p><p><strong>Results: </strong>Two thousand eighty hundred and thirty-six plateletpheresis procedures were done, out of which 666 (23.48%) were done on TA while 2170 (76.51%) were done on MCS +. Maximum donors, 1437 (55.66%) were in the 21-30 years category; Mean age was 30.75 years ± 8.44 standard deviation (SD); range18-65 years. Maximum donors 1185 (41.78%) were in the 61-70 kg category with mean weight - 74.33 kg ± 9.80 SD and mean height - 170.46 cm ± 4.99 SD only 4 (0.15%) donors were females. Two thousand six (70.73%) donors were voluntary, with 1620 (57.12%) repeat donors. Mean platelet count was 272.98 ± 56.59 × 10<sup>9</sup>/L with maximum donors having platelet count between 200 and 300 × 10<sup>9</sup>/L and ranged from 157 to 508 × 10<sup>9</sup>/L. Mean hemoglobin of donors - 14.87 g % ± 3.16 SD; total serum protein - 6.31 g/dl ± 4.8 SD. Mean platelet yield was 3.50 × 10<sup>11</sup> ± 0.71 SD; ranged from 2.9 to 7 × 10<sup>11</sup>. Plateletpheresis session profile of reactors and nonreactors showed that acid citrate dextrose used in reactors was more - 353.44 ml as compared to nonreactors - 311.72 ml. Reactors showed more volume of whole blood processed - 2899.43 ml as compared to nonreactors - 2601.63 ml. Time taken for completing the session was more in reactors - 82.40 mins as compared to nonreactors - 70.80 min. Platelet yield was 3.79 × 10<sup>11</sup> and 3.49 × 10<sup>11</sup> and plasma volume was 275.6 ml and 261.2 ml in reactors and nonreactors respectively.</p><p><strong>Conclusion: </strong>Demographics of plateletpheresis donors and session profile are vital for their safety.</p>","PeriodicalId":42296,"journal":{"name":"Asian Journal of Transfusion Science","volume":"19 1","pages":"99-103"},"PeriodicalIF":0.6000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364040/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Transfusion Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ajts.ajts_39_21","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/12/12 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Over decades, increased demand of platelet transfusions for patients with various conditions led to accelerated use of technologically advanced plateletpheresis.
Aims: Study the demographics of plateletpheresis donor and plateletpheresis session profile.
Setting and design: Prospective, cross-sectional, open label study.
Materials and methods: Plateletpheresis performed on Trima Accel (TA) and mechanical circulatory support (MCS) + during 2017-2018 on donors selected according to the guidelines.
Statistical analysis: SPSS (version 17) for windows statistical package.
Results: Two thousand eighty hundred and thirty-six plateletpheresis procedures were done, out of which 666 (23.48%) were done on TA while 2170 (76.51%) were done on MCS +. Maximum donors, 1437 (55.66%) were in the 21-30 years category; Mean age was 30.75 years ± 8.44 standard deviation (SD); range18-65 years. Maximum donors 1185 (41.78%) were in the 61-70 kg category with mean weight - 74.33 kg ± 9.80 SD and mean height - 170.46 cm ± 4.99 SD only 4 (0.15%) donors were females. Two thousand six (70.73%) donors were voluntary, with 1620 (57.12%) repeat donors. Mean platelet count was 272.98 ± 56.59 × 109/L with maximum donors having platelet count between 200 and 300 × 109/L and ranged from 157 to 508 × 109/L. Mean hemoglobin of donors - 14.87 g % ± 3.16 SD; total serum protein - 6.31 g/dl ± 4.8 SD. Mean platelet yield was 3.50 × 1011 ± 0.71 SD; ranged from 2.9 to 7 × 1011. Plateletpheresis session profile of reactors and nonreactors showed that acid citrate dextrose used in reactors was more - 353.44 ml as compared to nonreactors - 311.72 ml. Reactors showed more volume of whole blood processed - 2899.43 ml as compared to nonreactors - 2601.63 ml. Time taken for completing the session was more in reactors - 82.40 mins as compared to nonreactors - 70.80 min. Platelet yield was 3.79 × 1011 and 3.49 × 1011 and plasma volume was 275.6 ml and 261.2 ml in reactors and nonreactors respectively.
Conclusion: Demographics of plateletpheresis donors and session profile are vital for their safety.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
