Nicholas J Chan, Sarah Lentz, Paul A Gurr, Shereen Tan, Mona Schultebeyring, Sabine Rosenfeldt, Anna Schenk, Thomas Scheibel, Greg G Qiao
{"title":"Robust <i>β</i>-Sheet Peptide Reinforced Polymer Fibers.","authors":"Nicholas J Chan, Sarah Lentz, Paul A Gurr, Shereen Tan, Mona Schultebeyring, Sabine Rosenfeldt, Anna Schenk, Thomas Scheibel, Greg G Qiao","doi":"10.1002/smsc.202500115","DOIUrl":null,"url":null,"abstract":"<p><p>In natural silks, <i>β</i>-sheet crystals are embedded within an amorphous matrix resulting in polypeptide-based nanocomposites. These <i>β</i>-sheet crystals contribute to the subsequent high strength and toughness of spider silk. Consequently, imitation and mimicry of such concepts utilizing polypeptides provide a pathway toward putatively achieving similar properties. Herein, the introduction of poly(l-valine) (PVal) <i>β</i>-sheet nanocrystals into different fibers is investigated. Analysis of micro- and nanoscale features shows that polyvaline <i>β</i>-sheets could be implemented into fibers made from different polymer classes, ranging from standard polymers (polycaprolactone (PCL), Nylon 6) to biopolymers like cellulose and recombinant spider silk. The in situ implementation of PVal during wet-spinning leads to a significant change in the resulting mechanical properties, depending on the polymer used.</p>","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 8","pages":"2500115"},"PeriodicalIF":8.3000,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362809/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Small Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/smsc.202500115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
In natural silks, β-sheet crystals are embedded within an amorphous matrix resulting in polypeptide-based nanocomposites. These β-sheet crystals contribute to the subsequent high strength and toughness of spider silk. Consequently, imitation and mimicry of such concepts utilizing polypeptides provide a pathway toward putatively achieving similar properties. Herein, the introduction of poly(l-valine) (PVal) β-sheet nanocrystals into different fibers is investigated. Analysis of micro- and nanoscale features shows that polyvaline β-sheets could be implemented into fibers made from different polymer classes, ranging from standard polymers (polycaprolactone (PCL), Nylon 6) to biopolymers like cellulose and recombinant spider silk. The in situ implementation of PVal during wet-spinning leads to a significant change in the resulting mechanical properties, depending on the polymer used.
期刊介绍：
Small Science is a premium multidisciplinary open access journal dedicated to publishing impactful research from all areas of nanoscience and nanotechnology. It features interdisciplinary original research and focused review articles on relevant topics. The journal covers design, characterization, mechanism, technology, and application of micro-/nanoscale structures and systems in various fields including physics, chemistry, materials science, engineering, environmental science, life science, biology, and medicine. It welcomes innovative interdisciplinary research and its readership includes professionals from academia and industry in fields such as chemistry, physics, materials science, biology, engineering, and environmental and analytical science. Small Science is indexed and abstracted in CAS, DOAJ, Clarivate Analytics, ProQuest Central, Publicly Available Content Database, Science Database, SCOPUS, and Web of Science.
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