Xenotransplantation Literature Update: January-June 2025.

IF 4.1 4区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Xenotransplantation Pub Date : 2025-07-01 DOI:10.1111/xen.70072

Kasra Shirini, Joseph M Ladowski, Raphael P H Meier

引用次数: 0

Abstract

From January to June 2025, the field of xenotransplantation progressed rapidly toward clinical translation, with landmark compassionate-use cases, peer-reviewed reports of porcine kidney, heart, and liver transplants in humans, and the release of authoritative international guidelines. This literature update summarizes key developments across clinical trials, immunological insights, donor engineering, preservation strategies, infection control, and ethical frameworks, highlighting a growing consensus on the scientific and regulatory roadmap for safe, effective, and equitable xenotransplantation.

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异种移植文献更新：2025年1 - 6月。

从2025年1月到6月，异种移植领域迅速向临床转化发展，具有里程碑意义的同情用例，人类猪肾，心脏和肝脏移植的同行评审报告，以及权威国际指南的发布。本文献更新总结了临床试验、免疫学见解、供体工程、保存策略、感染控制和伦理框架等方面的关键进展，强调了在安全、有效和公平的异种移植的科学和监管路线图上日益达成的共识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Xenotransplantation 医学-医学：研究与实验

CiteScore

6.80

自引率

15.40%

发文量

审稿时长

>12 weeks

期刊介绍： Xenotransplantation provides its readership with rapid communication of new findings in the field of organ and tissue transplantation across species barriers.The journal is not only of interest to those whose primary area is xenotransplantation, but also to veterinarians, microbiologists and geneticists. It also investigates and reports on the controversial theological, ethical, legal and psychological implications of xenotransplantation.