Leveraging phagocytosis using nanomedicines for cancer immunotherapy.

IF 17.5 1区医学 Q1 ONCOLOGY

Trends in cancer Pub Date : 2025-08-26 DOI:10.1016/j.trecan.2025.08.004

Susam Lee, Hoyeon Nam, Katelyn Wahl, Heewon Park, DaeYong Lee

引用次数: 0

Abstract

Phagocytosis upregulation plays a crucial role in bridging to adaptive immunity for cancer immunotherapy. However, current approaches to modulating phagocytosis are beneficial to certain types of cancer only. In this Forum paper, we will highlight how nanoengineering can overcome the current limitation of phagocytosis-mediated cancer immunotherapy.

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利用纳米药物利用吞噬作用进行癌症免疫治疗。

在肿瘤免疫治疗中，吞噬上调在桥接适应性免疫中起着至关重要的作用。然而，目前调节吞噬作用的方法仅对某些类型的癌症有益。在这篇论坛论文中，我们将重点介绍纳米工程如何克服目前吞噬介导的癌症免疫治疗的局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in cancer Medicine-Oncology

CiteScore

28.50

自引率

0.50%

发文量

138

期刊介绍： Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.