{"title":"Entropy-based risk network identification in adolescent self-injurious behavior using machine learning and network analysis.","authors":"Zheng Zhang, Honghui Chen, Yanyue Ye, Hui Chen, Huijuan Guo, Jiansong Zhou","doi":"10.1038/s41398-025-03511-3","DOIUrl":null,"url":null,"abstract":"<p><p>Adolescent Self-Injurious Behavior (SIB) is a significant global public health issue, with a lifetime prevalence rate of approximately 13.7%. As awareness of SIB rises, there is an urgent need for effective prediction mechanisms to enable early identification and intervention, reducing the risk of suicide and self-harm attempts. This study, grounded in Psychopathological Network Theory, uses machine learning and network analysis to explore the multidimensional structure of risk factors for adolescent SIB. A survey of 2047 adolescents aged 11 to 17 years in China analyzed 19 variables across physiological, psychological, and social domains. The Entropy Weight Method (EWM) was applied to combine network analysis and machine learning outcomes for a comprehensive risk evaluation. The study identified key risk factors for SIB, including loneliness, ADHD symptoms, Internet addiction, anxiety, depression, affinity for solitude, autistic traits, being bullied. These factors interact within a complex network structure, influencing the occurrence of SIB both directly and indirectly. The integration of EWM, network analysis, and machine learning provides a more precise risk assessment approach for adolescent SIB. The findings offer valuable insights into the causal mechanisms of SIB and emphasize the importance of targeted prevention and intervention strategies.</p>","PeriodicalId":23278,"journal":{"name":"Translational Psychiatry","volume":"15 1","pages":"299"},"PeriodicalIF":6.2000,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12368204/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41398-025-03511-3","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
Adolescent Self-Injurious Behavior (SIB) is a significant global public health issue, with a lifetime prevalence rate of approximately 13.7%. As awareness of SIB rises, there is an urgent need for effective prediction mechanisms to enable early identification and intervention, reducing the risk of suicide and self-harm attempts. This study, grounded in Psychopathological Network Theory, uses machine learning and network analysis to explore the multidimensional structure of risk factors for adolescent SIB. A survey of 2047 adolescents aged 11 to 17 years in China analyzed 19 variables across physiological, psychological, and social domains. The Entropy Weight Method (EWM) was applied to combine network analysis and machine learning outcomes for a comprehensive risk evaluation. The study identified key risk factors for SIB, including loneliness, ADHD symptoms, Internet addiction, anxiety, depression, affinity for solitude, autistic traits, being bullied. These factors interact within a complex network structure, influencing the occurrence of SIB both directly and indirectly. The integration of EWM, network analysis, and machine learning provides a more precise risk assessment approach for adolescent SIB. The findings offer valuable insights into the causal mechanisms of SIB and emphasize the importance of targeted prevention and intervention strategies.
期刊介绍:
Psychiatry has suffered tremendously by the limited translational pipeline. Nobel laureate Julius Axelrod''s discovery in 1961 of monoamine reuptake by pre-synaptic neurons still forms the basis of contemporary antidepressant treatment. There is a grievous gap between the explosion of knowledge in neuroscience and conceptually novel treatments for our patients. Translational Psychiatry bridges this gap by fostering and highlighting the pathway from discovery to clinical applications, healthcare and global health. We view translation broadly as the full spectrum of work that marks the pathway from discovery to global health, inclusive. The steps of translation that are within the scope of Translational Psychiatry include (i) fundamental discovery, (ii) bench to bedside, (iii) bedside to clinical applications (clinical trials), (iv) translation to policy and health care guidelines, (v) assessment of health policy and usage, and (vi) global health. All areas of medical research, including — but not restricted to — molecular biology, genetics, pharmacology, imaging and epidemiology are welcome as they contribute to enhance the field of translational psychiatry.