{"title":"DNA Photofluids: An Innovative Breakthrough in Mimicking Cellular Life Behaviors.","authors":"Rui Wang, Wenguo Cui, Xinliang Chen","doi":"10.34133/research.0845","DOIUrl":null,"url":null,"abstract":"<p><p>Current molecular machines face substantial challenges in coordinating their actions in space and time to generate cell-like macroscopic motions. A recent study in <i>Nature Materials</i> introduced a light-responsive artificial DNA nanomachine based on liquid-liquid phase separation technology-photofluids. By applying different light stimuli for spatiotemporal control, this nanomachine system successfully mimics typical cellular behaviors such as division, deformation, pseudopod extension, and rotation at the macroscopic scale for the first time. This study represents an innovative pathway from energy conversion at the molecular level to cell-like motion at the macroscopic level.</p>","PeriodicalId":21120,"journal":{"name":"Research","volume":"8 ","pages":"0845"},"PeriodicalIF":10.7000,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370175/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.34133/research.0845","RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"Multidisciplinary","Score":null,"Total":0}
引用次数: 0
Abstract
Current molecular machines face substantial challenges in coordinating their actions in space and time to generate cell-like macroscopic motions. A recent study in Nature Materials introduced a light-responsive artificial DNA nanomachine based on liquid-liquid phase separation technology-photofluids. By applying different light stimuli for spatiotemporal control, this nanomachine system successfully mimics typical cellular behaviors such as division, deformation, pseudopod extension, and rotation at the macroscopic scale for the first time. This study represents an innovative pathway from energy conversion at the molecular level to cell-like motion at the macroscopic level.
期刊介绍:
Research serves as a global platform for academic exchange, collaboration, and technological advancements. This journal welcomes high-quality research contributions from any domain, with open arms to authors from around the globe.
Comprising fundamental research in the life and physical sciences, Research also highlights significant findings and issues in engineering and applied science. The journal proudly features original research articles, reviews, perspectives, and editorials, fostering a diverse and dynamic scholarly environment.