Comparing dose response of cancer incidence in Sweden after the Chernobyl Nuclear Power Plant accident with Life Span Study of atomic bomb survivors.

IF 0.7 4区环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES

Radiation protection dosimetry Pub Date : 2025-10-06 DOI:10.1093/rpd/ncaf097

Martin Tondel, Tobias Nordquist, Mats Isaksson, Christopher Rääf, Robert Wålinder

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Abstract

Follow-up of the atomic bomb survivors in Japan in the Life Span Study (LSS) has been fundamental for the understanding of the dose-response curve. We compare our risk estimates from a newly published epidemiological study on cancer in Sweden after the Chernobyl Nuclear Power Plant accident with the LSS data. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) were calculated using conditional logistic regression adjusted for rural/nonrural habitat, education level, and pre-Chernobyl cancer incidence from 1980 to 1985, respectively. Adjusted HRs by sex were calculated in deciles for all cancer sites combined for 1986 to 2020. These risk estimates were translated to excess relative risk (ERR) to allow comparison with LSS incidence data. ERRs per decile were compatible with ERR in the low-dose range <100 mGy for both sexes. The CIs in each decile need to be taken into account when interpreting the dose-response curve. Risk estimates in dose categories add important information at very low doses on the dose-response curve when compared to LSS data.

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瑞典切尔诺贝利核电站事故后癌症发病率的剂量反应与原子弹幸存者寿命研究的比较。

在寿命研究（LSS）中对日本原子弹幸存者的随访是了解剂量-反应曲线的基础。我们将切尔诺贝利核电站事故后瑞典最新发表的癌症流行病学研究的风险估计与LSS的数据进行了比较。分别利用1980 - 1985年农村/非农村生境、教育水平和切尔诺贝利前癌症发病率调整后的条件logistic回归计算95%置信区间（95% ci）的风险比（hr）。按性别调整后的hr以十分位数计算1986年至2020年所有癌症部位的总和。这些风险估计被转化为超额相对风险（ERR），以便与LSS发生率数据进行比较。每十分位误差与低剂量范围内的误差一致

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来源期刊

Radiation protection dosimetry 环境科学-公共卫生、环境卫生与职业卫生

CiteScore

1.40

自引率

10.00%

发文量

223

审稿时长

6-12 weeks

期刊介绍： Radiation Protection Dosimetry covers all aspects of personal and environmental dosimetry and monitoring, for both ionising and non-ionising radiations. This includes biological aspects, physical concepts, biophysical dosimetry, external and internal personal dosimetry and monitoring, environmental and workplace monitoring, accident dosimetry, and dosimetry related to the protection of patients. Particular emphasis is placed on papers covering the fundamentals of dosimetry; units, radiation quantities and conversion factors. Papers covering archaeological dating are included only if the fundamental measurement method or technique, such as thermoluminescence, has direct application to personal dosimetry measurements. Papers covering the dosimetric aspects of radon or other naturally occurring radioactive materials and low level radiation are included. Animal experiments and ecological sample measurements are not included unless there is a significant relevant content reason.