{"title":"Validity and reliability of the Mini International Neuropsychiatric Interview in Sub-Saharan Africa: a cross-country comparison study.","authors":"Kristina J Korte, Kimberly Hook, Rocky Stroud, Amantia Ametaj, Manasi Sharma, Hayden Mountcastle, Biruh Alemayehu, Beakal Amare, Azeb Asaminew Alemu, Ribka Birhanu, Engida Girma, Barkot Milkias, Mahlet Yared, Florence Jaguga, Jackline Mmochi, Felitcita Omari, Edgar Guma, Hillary Kutessa, Claire Kwagala, Harriet Nakuya, Molly Naisanga, Dickens Akena, Lukoye Atwoli, Symon Kariuki, Charles R J C Newton, Zukiswa Zingela, Dan J Stein, Teferra Solomon, Karestan C Koenen, Bizu Gelaye","doi":"10.1017/S0033291725100573","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Diagnostic tools, such as the Mini International Neuropsychiatric Interview (MINI) 7.0.2 and the Structured Clinical Interview for the DSM-5 (SCID), aim to increase the validity and reliability of diagnostic assessment. However, these tools were created in high-income countries (HICs) with limited investigation of the psychometrics of these tools when used in low- and middle-income countries (LMICs). Thus, there is a need to examine the psychometric properties of these measures in LMICs. The present investigation aimed to examine the use of the MINI in Ethiopia, Kenya, and Uganda.</p><p><strong>Methods: </strong>A multicountry comparison of the validity and reliability of the MINI was conducted in a study of 954 participants (<i>n</i> = 667 cases; <i>n</i> = 287 controls) with and without a psychotic spectrum disorder, defined as any psychotic or bipolar spectrum disorder for the NeuroGAP - Psychosis study. Test-retest reliability of the MINI was examined in a subset of 303 participants (<i>n</i> = 164 cases; <i>n</i> = 139 controls) from the overall sample.</p><p><strong>Results: </strong>Results revealed the MINI and SCID provided excellent diagnostic accuracy with area under the curve (AUC) values of .91 (<i>SE</i> = .01) for the MINI and .95 (<i>SE</i> = .01) for the SCID. Positive predictive values (PPV) were the highest for the SCID (93.8%) and slightly lower for the MINI (88.7%). Reliability analyses revealed substantial agreement for psychotic and bipolar diagnostic groups.</p><p><strong>Conclusions: </strong>Similar patterns of results were observed at the country level with a few notable differences. Limitations and future directions are discussed.</p>","PeriodicalId":20891,"journal":{"name":"Psychological Medicine","volume":"55 ","pages":"e254"},"PeriodicalIF":5.5000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453114/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychological Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/S0033291725100573","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Diagnostic tools, such as the Mini International Neuropsychiatric Interview (MINI) 7.0.2 and the Structured Clinical Interview for the DSM-5 (SCID), aim to increase the validity and reliability of diagnostic assessment. However, these tools were created in high-income countries (HICs) with limited investigation of the psychometrics of these tools when used in low- and middle-income countries (LMICs). Thus, there is a need to examine the psychometric properties of these measures in LMICs. The present investigation aimed to examine the use of the MINI in Ethiopia, Kenya, and Uganda.
Methods: A multicountry comparison of the validity and reliability of the MINI was conducted in a study of 954 participants (n = 667 cases; n = 287 controls) with and without a psychotic spectrum disorder, defined as any psychotic or bipolar spectrum disorder for the NeuroGAP - Psychosis study. Test-retest reliability of the MINI was examined in a subset of 303 participants (n = 164 cases; n = 139 controls) from the overall sample.
Results: Results revealed the MINI and SCID provided excellent diagnostic accuracy with area under the curve (AUC) values of .91 (SE = .01) for the MINI and .95 (SE = .01) for the SCID. Positive predictive values (PPV) were the highest for the SCID (93.8%) and slightly lower for the MINI (88.7%). Reliability analyses revealed substantial agreement for psychotic and bipolar diagnostic groups.
Conclusions: Similar patterns of results were observed at the country level with a few notable differences. Limitations and future directions are discussed.
期刊介绍:
Now in its fifth decade of publication, Psychological Medicine is a leading international journal in the fields of psychiatry, related aspects of psychology and basic sciences. From 2014, there are 16 issues a year, each featuring original articles reporting key research being undertaken worldwide, together with shorter editorials by distinguished scholars and an important book review section. The journal''s success is clearly demonstrated by a consistently high impact factor.