Physical Function and Mobility in Older Adults Receiving Treatment for Acute Myeloid Leukemia: A Longitudinal Qualitative Study.

IF 1.4 4区医学 Q2 NURSING

Oncology nursing forum Pub Date : 2025-08-18 DOI:10.1188/25.ONF.382-392

Ahrang Jung, Victoria Crowder, Ya-Ning Chan, Dawn Klemm, Kelly R Tan, Elissa Herman Poor, Ayomide Okanlawon Bankole, Danielle Steele Anderson, Susan Coppola, Mackenzi Pergolotti, Todd A Schwartz, Daniel R Richardson, Ashley Leak Bryant

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引用次数: 0

Abstract

Purpose: To explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating agent and venetoclax (HMA + VEN).

Participants & setting: Participants were older adults with AML (N = 17) receiving HMA + VEN at a comprehensive cancer center. Most were male and aged 64-89 years (median age = 75 years).

Methodologic approach: This study used a longitudinal qualitative approach with semistructured interviews at cycles 1, 2, and 7 of chemotherapy. Interviews were audio recorded, transcribed, coded, and analyzed using thematic analysis.

Findings: Four themes were identified: reduced mobility and limited options for physical activities (cycle 1), periodic changes in mobility and energy level (cycle 2), acceptance and adaptation to changed mobility (cycle 7), and strategies to stay active.

Implications for nursing: Substantial challenges with physical function and mobility exist for older adults undergoing treatment for AML. Oncology nurses should anticipate patient needs, provide appropriate care, and make referrals to address physical and functional needs before and during HMA + VEN treatment.

查看原文本刊更多论文

接受急性髓性白血病治疗的老年人的身体功能和活动能力：一项纵向定性研究。

目的：探讨老年（60岁或以上）急性髓性白血病（AML）患者在使用低甲基化药物和venetoclax （HMA + VEN）治疗期间的三个时间点对身体功能和活动能力的看法。参与者和环境：参与者是在综合癌症中心接受HMA + VEN治疗的老年AML患者（N = 17）。大多数为男性，年龄64-89岁（中位年龄= 75岁）。方法学：本研究采用纵向定性方法，在化疗第1、2和7周期进行半结构化访谈。访谈被录音、转录、编码，并使用主题分析进行分析。研究结果：确定了四个主题：活动能力降低和体育活动选择有限（周期1），活动能力和能量水平的周期性变化（周期2），接受和适应变化的活动能力（周期7），以及保持活跃的策略。护理意义：接受急性髓性白血病治疗的老年人存在身体功能和活动能力方面的重大挑战。肿瘤护士应该在HMA + VEN治疗之前和期间预测患者的需求，提供适当的护理，并转诊以解决患者的身体和功能需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oncology nursing forum 医学-护理

CiteScore

3.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The mission of the Oncology Nursing Forum, an official publication of ONS, is to Convey research information related to practice, technology, education, and leadership. Disseminate oncology nursing research and evidence-based practice to enhance transdisciplinary quality cancer care. Stimulate discussion of critical issues relevant to oncology nursing.