A Case of Measles Virus-caused Subacute Sclerosing Panencephalitis Diagnosed by Molecular and Clinical Analysis.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2025-08-28 eCollection Date: 2025-08-01 DOI:10.1093/ofid/ofaf453

Tingyan Liu, Caiyan Zhang, Meixiu Ming, Lian Chen, Weiming Chen, Yang Xu, Meili Shen, Jia Liu, Qiuxiang Ou, Hua Bao, Xiangjun Chen, Guoping Lu, Gangfeng Yan

引用次数: 0

Abstract

Subacute sclerosing panencephalitis (SSPE) is a rare and lethal neurodegenerative encephalitis caused by persistent measles virus infection. We report an SSPE case in a patient infected at 6 months old, diagnosed using clinical methods and metagenomic sequencing, highlighting the benefits of combining clinical and molecular techniques for improved diagnosis.

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麻疹病毒致亚急性硬化性全脑炎1例分子及临床分析。

亚急性硬化性全脑炎（SSPE）是一种罕见的致死性神经退行性脑炎，由持续的麻疹病毒感染引起。我们报告了一个6个月大感染的SSPE病例，使用临床方法和宏基因组测序进行诊断，突出了临床和分子技术相结合的好处，以改进诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.