Epigenetic signature of depression susceptibility in cortical astrocytes.

IF 15 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-08-20 DOI:10.1016/j.neuron.2025.07.019

Yihui Cui

引用次数: 0

Abstract

In this issue of Neuron, Fulton et al.¹ discover ZBTB7A, a chromatin regulator in orbitofrontal astrocytes, drives neuronal hyperactivity to promote depression susceptibility.

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皮层星形胶质细胞抑郁易感性的表观遗传学特征。

在这一期的《神经元》杂志上，Fulton等人发现ZBTB7A，一种眼窝额叶星形胶质细胞中的染色质调节因子，驱动神经元过度活跃，促进抑郁易感性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.