Minimally invasive microvascular decompression for trigeminal neuralgia: results and complication avoidance in a consecutive series of patients.

IF 3 2区 医学 Q2 CLINICAL NEUROLOGY
Francesco Tomasello, Massimiliano Salvatore Cardali, Filippo Flavio Angileri, Alberto Romano, Domenico La Torre
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引用次数: 0

Abstract

Objective: Microvascular decompression (MVD) represents a milestone for the treatment of trigeminal neuralgia (TN). Nevertheless, several complications still occur and may negatively affect the outcome. The authors recently proposed a minimally invasive technique, including endoscopic assistance in instances of intraoperative hidden corners, with which they were able to achieve good results in terms of pain relief and minimize overall complication rates. The aim of this study was to verify the short- and long-term efficacy of the proposed refinement of the standard MVD technique in terms of pain relief and reduction of complication rates.

Methods: The authors analyzed the surgical and outcome data of 154 consecutive patients with TN over a 10-year period. Outcome variables included pain relief, facial numbness, muscular atrophy, local cutaneous occipital and temporal pain or numbness, cerebellar injury, hearing loss, cranial nerve deficits, wound infection, CSF leakage, recurrences, and mortality rate. The overall complication rate was defined as the occurrence of any of the aforementioned items.

Results: A total of 154 consecutive patients were included in the study. Pain relief was achieved in 97.4% immediately after surgery, while 92.9%, 85.7%, and 83.1% of patients were pain free at the 1-year, 5-year, and last follow-up, respectively. The mean follow-up was 71.18 months (range 11-120 months). The overall complication rate was 5.8%, but only 1.3% of patients experienced permanent neurological complications. The CSF leakage rate was 3.2%. Two patients (1.3%) developed complete hearing loss, and another patient developed mild temporary dysfunction of the eighth cranial nerve. One patient experienced postoperative ataxia but completely recovered in 1 month. No other complication or death was observed.

Conclusions: The proposed minimally invasive refinement of the standard MVD technique has been shown to be effective in maintaining excellent results in terms of pain relief, in both the short and long term, while minimizing the overall complication rate associated with this surgical approach.

微创微血管减压治疗三叉神经痛:连续系列患者的结果和并发症避免。
目的:微血管减压(MVD)是三叉神经痛(TN)治疗的一个里程碑。然而,一些并发症仍然会发生,并可能对结果产生负面影响。作者最近提出了一种微创技术,包括术中隐藏角落的内镜辅助,他们能够在缓解疼痛和减少总体并发症方面取得良好的效果。本研究的目的是验证标准MVD技术在缓解疼痛和减少并发症发生率方面的短期和长期疗效。方法:作者分析了154例连续10年的TN患者的手术和预后资料。结果变量包括疼痛缓解、面部麻木、肌肉萎缩、局部皮肤枕部和颞部疼痛或麻木、小脑损伤、听力丧失、颅神经缺损、伤口感染、脑脊液漏、复发和死亡率。总并发症发生率定义为出现上述任何一项。结果:共有154例连续患者纳入研究。97.4%的患者术后立即疼痛缓解,92.9%、85.7%和83.1%的患者在1年、5年和最后一次随访时疼痛消失。平均随访时间为71.18个月(11 ~ 120个月)。总体并发症发生率为5.8%,但只有1.3%的患者出现永久性神经系统并发症。脑脊液渗漏率为3.2%。2例患者(1.3%)出现完全性听力损失,1例患者出现第8脑神经轻度暂时性功能障碍。1例患者术后出现共济失调,1个月后完全恢复。无其他并发症或死亡。结论:所提出的标准MVD技术的微创改进已被证明在短期和长期保持良好的疼痛缓解效果方面是有效的,同时将与该手术入路相关的总并发症发生率降至最低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neurosurgical focus
Neurosurgical focus CLINICAL NEUROLOGY-SURGERY
CiteScore
6.30
自引率
0.00%
发文量
261
审稿时长
3 months
期刊介绍: Information not localized
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