Efficacy of microvascular decompression in the treatment of trigeminal neuralgia: a retrospective Single-Center study of 28 cases.

IF 2.5 3区 医学 Q2 CLINICAL NEUROLOGY
Anastasija Krzemińska, Marta Koźba-Gosztyła, Joanna Bladowska, Bogdan Czapiga
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引用次数: 0

Abstract

Objective: To evaluate the effectiveness, safety, and patient satisfaction associated with microvascular decompression (MVD) in the treatment of trigeminal neuralgia (TN), and to identify clinical and surgical factors associated with postoperative outcomes and TN recurrence.

Methods: This retrospective single-center study included 28 patients with TN who underwent MVD between 2018 and 2025. Data on demographics, TN subtype, preoperative imaging, prior treatments, surgical findings, use of Teflon suture, and complications were analyzed. Outcomes were assessed using the Barrow Neurological Institute (BNI) Pain Intensity Scale at early postoperative and follow-up stages. Kaplan-Meier survival analysis was used to assess pain-free intervals. Patient satisfaction was evaluated based on willingness to undergo the surgery again.

Results: Classical TN was diagnosed in 75% of patients. Preoperative MRI correctly predicted the presence of a conflict in 20 of 26 patients who actually had one (76.9%). Immediate postoperative pain relief (BNI I-II) was achieved in 85.7% of patients, and recurrence occurred in 16.7% of initially pain-free individuals. The average pain-free period was 28.5 ± 29.4 months. The use of a Teflon suture did not significantly affect recurrence or outcome. Major complications occurred in 10.7% of cases and included CSF leak from the surgical wound, neuroinfection and hematoma. Patient satisfaction was high, with 82% stating they would choose to undergo MVD again. Better outcomes were significantly associated with classical TN subtype. No significant associations were found with age, sex, prior gamma knife therapy, or Teflon fixation technique.

Conclusions: in our cohort MVD was a highly effective and well-tolerated treatment for TN, particularly in classical cases, offering high rates of long-term pain relief and patient satisfaction. Complications were rare in our cohort. Outcomes were not influenced by Teflon suture use or demographic factors, supporting the role of MVD as a first-line surgical option in appropriate candidates.

Clinical trial number: Not applicable.

微血管减压治疗三叉神经痛28例回顾性单中心研究
目的:评价微血管减压术(MVD)治疗三叉神经痛(TN)的有效性、安全性和患者满意度,并探讨影响三叉神经痛术后疗效和复发的临床和外科因素。方法:本回顾性单中心研究纳入了2018年至2025年间行MVD的28例TN患者。我们分析了人口统计学、TN亚型、术前影像学、既往治疗、手术结果、特氟龙缝线的使用和并发症的数据。术后早期和随访阶段采用巴罗神经学研究所(BNI)疼痛强度量表评估结果。Kaplan-Meier生存分析用于评估无痛时间间隔。患者满意度是根据再次接受手术的意愿来评估的。结果:75%的患者诊断为典型TN。术前MRI正确预测了26例实际存在冲突的患者中的20例(76.9%)。85.7%的患者术后疼痛立即缓解(BNI I-II), 16.7%的患者出现复发。平均无痛期28.5±29.4个月。使用聚四氟乙烯缝线对复发或预后没有显著影响。10.7%的病例发生主要并发症,包括手术伤口脑脊液漏、神经感染和血肿。患者满意度很高,82%的人表示他们会选择再次接受MVD。经典TN亚型患者预后较好。未发现年龄、性别、既往伽玛刀治疗或特氟龙固定技术有显著相关性。结论:在我们的队列中,MVD是一种非常有效且耐受性良好的治疗TN的方法,特别是在经典病例中,提供了高的长期疼痛缓解率和患者满意度。并发症在我们的队列中很少见。结果不受聚四氟乙烯缝线使用或人口统计学因素的影响,支持MVD作为合适候选人一线手术选择的作用。临床试验号:不适用。
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来源期刊
Neurosurgical Review
Neurosurgical Review 医学-临床神经学
CiteScore
5.60
自引率
7.10%
发文量
191
审稿时长
6-12 weeks
期刊介绍: The goal of Neurosurgical Review is to provide a forum for comprehensive reviews on current issues in neurosurgery. Each issue contains up to three reviews, reflecting all important aspects of one topic (a disease or a surgical approach). Comments by a panel of experts within the same issue complete the topic. By providing comprehensive coverage of one topic per issue, Neurosurgical Review combines the topicality of professional journals with the indepth treatment of a monograph. Original papers of high quality are also welcome.
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