Chad A. Mirkin*, Sarah Hurst Petrosko, Natalie Artzi, Koray Aydin, Austin Biaggne, C. Jeffrey Brinker, Katherine E. Bujold, Y. Charles Cao, Rachel R. Chan, Chaojian Chen, Peng-Cheng Chen, Xiaodong Chen, Olivier J. G. L. Chevalier, Chung Hang Jonathan Choi, Richard M. Crooks, Vinayak P. Dravid, Jingshan S. Du, Sasha B. Ebrahimi, Hongyou Fan, Omar K. Farha, C. Adrian Figg, Tanner D. Fink, Connor M. Forsyth, Harald Fuchs, Franz M. Geiger, Nathan C. Gianneschi, Kyle J. Gibson, David S. Ginger, SiShi Guo, Justin S. Hanes, Liangliang Hao, Jin Huang, Bryan M. Hunter, Fengwei Huo, Jeongmin Hwang, Rongchao Jin, Shana O. Kelley, Thomas J. Kempa, Youngeun Kim, Sergej Kudruk, Sneha Kumari, Kaitlin M. Landy, Ki-Bum Lee, Noel J. Leon, Jun Li, Yuanwei Li, Zhiwei Li, Bin Liu, Guoliang Liu, Xiaogang Liu, Luis M. Liz-Marzán, Jochen H. Lorch, Taokun Luo, Robert J. Macfarlane, Jill E. Millstone, Milan Mrksich, Catherine J. Murphy, Rajesh R. Naik, Andre E. Nel, Christopher Oetheimer, Jenny K. Hedlund Orbeck, So-Jung Park, Benjamin E. Partridge, Nicholas A. Peppas, Michelle L. Personick, Arindam Raj, Namrata Ramani, Michael B. Ross, Stacey Barnaby Ross, Edward H. Sargent, Tanushri Sengupta, George C. Schatz, Dwight S. Seferos, Tamar Seideman, Soyoung Eileen Seo, Bo Shen, Wooyoung Shim, Donghoon Shin, Ulrich Simon, Andrew J. Sinegra, Peter T. Smith, Alexander M. Spokoyny, Peter J. Stang, Alexander H. Stegh, J. Fraser Stoddart, Dayne F. Swearer, Weihong Tan, Michelle H. Teplensky, C. Shad Thaxton, David R. Walt, Mary X. Wang, Zhe Wang, Wei David Wei, Paul S. Weiss, Peter H. Winegar, Younan Xia, Yi Xie, Xiaoyang Xu, Peidong Yang, Yiming Yang, Zihao Ye, Kuk Ro Yoon, Cuizheng Zhang, Hua Zhang, Ke Zhang, Liangfang Zhang, Xiaoyu Zhang, Ye Zhang, Zijian Zheng, Wenjie Zhou, Shengshuang Zhu and Wei Zhu,
{"title":"33 Unresolved Questions in Nanoscience and Nanotechnology","authors":"Chad A. Mirkin*, Sarah Hurst Petrosko, Natalie Artzi, Koray Aydin, Austin Biaggne, C. Jeffrey Brinker, Katherine E. Bujold, Y. Charles Cao, Rachel R. Chan, Chaojian Chen, Peng-Cheng Chen, Xiaodong Chen, Olivier J. G. L. Chevalier, Chung Hang Jonathan Choi, Richard M. Crooks, Vinayak P. Dravid, Jingshan S. Du, Sasha B. Ebrahimi, Hongyou Fan, Omar K. Farha, C. Adrian Figg, Tanner D. Fink, Connor M. Forsyth, Harald Fuchs, Franz M. Geiger, Nathan C. Gianneschi, Kyle J. Gibson, David S. Ginger, SiShi Guo, Justin S. Hanes, Liangliang Hao, Jin Huang, Bryan M. Hunter, Fengwei Huo, Jeongmin Hwang, Rongchao Jin, Shana O. Kelley, Thomas J. Kempa, Youngeun Kim, Sergej Kudruk, Sneha Kumari, Kaitlin M. Landy, Ki-Bum Lee, Noel J. Leon, Jun Li, Yuanwei Li, Zhiwei Li, Bin Liu, Guoliang Liu, Xiaogang Liu, Luis M. Liz-Marzán, Jochen H. Lorch, Taokun Luo, Robert J. Macfarlane, Jill E. Millstone, Milan Mrksich, Catherine J. Murphy, Rajesh R. Naik, Andre E. Nel, Christopher Oetheimer, Jenny K. Hedlund Orbeck, So-Jung Park, Benjamin E. Partridge, Nicholas A. Peppas, Michelle L. Personick, Arindam Raj, Namrata Ramani, Michael B. Ross, Stacey Barnaby Ross, Edward H. Sargent, Tanushri Sengupta, George C. Schatz, Dwight S. Seferos, Tamar Seideman, Soyoung Eileen Seo, Bo Shen, Wooyoung Shim, Donghoon Shin, Ulrich Simon, Andrew J. Sinegra, Peter T. Smith, Alexander M. Spokoyny, Peter J. Stang, Alexander H. Stegh, J. Fraser Stoddart, Dayne F. Swearer, Weihong Tan, Michelle H. Teplensky, C. Shad Thaxton, David R. Walt, Mary X. Wang, Zhe Wang, Wei David Wei, Paul S. Weiss, Peter H. Winegar, Younan Xia, Yi Xie, Xiaoyang Xu, Peidong Yang, Yiming Yang, Zihao Ye, Kuk Ro Yoon, Cuizheng Zhang, Hua Zhang, Ke Zhang, Liangfang Zhang, Xiaoyu Zhang, Ye Zhang, Zijian Zheng, Wenjie Zhou, Shengshuang Zhu and Wei Zhu, ","doi":"10.1021/acsnano.5c12854","DOIUrl":null,"url":null,"abstract":"<p >Significant advances in science and engineering often emerge at the intersections of disciplines. Nanoscience and nanotechnology are inherently interdisciplinary, uniting researchers from chemistry, physics, biology, medicine, materials science, and engineering. This convergence has fostered novel ways of thinking and enabled the development of materials, tools, and technologies that have transformed both basic and applied research, as well as how we address critical societal challenges. In this Nano Focus, we pose and explore 33 questions whose answers could profoundly impact fields such as energy, electronics, the environment, optics, and medicine. These questions highlight the need for deeper foundational understanding, improved tools and techniques, and innovative applications─each with significant societal relevance. Together, they represent a global call-to-action for the scientific community.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"19 36","pages":"31933–31968"},"PeriodicalIF":16.0000,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Nano","FirstCategoryId":"88","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsnano.5c12854","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Significant advances in science and engineering often emerge at the intersections of disciplines. Nanoscience and nanotechnology are inherently interdisciplinary, uniting researchers from chemistry, physics, biology, medicine, materials science, and engineering. This convergence has fostered novel ways of thinking and enabled the development of materials, tools, and technologies that have transformed both basic and applied research, as well as how we address critical societal challenges. In this Nano Focus, we pose and explore 33 questions whose answers could profoundly impact fields such as energy, electronics, the environment, optics, and medicine. These questions highlight the need for deeper foundational understanding, improved tools and techniques, and innovative applications─each with significant societal relevance. Together, they represent a global call-to-action for the scientific community.
期刊介绍：
ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.
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