Construction of Hierarchical Star Like Morphology of NiO Nanosheets Having Superb Peroxidase Mimetic Properties for Effective Colorimetric H2O2 Sensing.

IF 3.1 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS
Mohib Ullah, Jasgurpreet Singh Chohan, Prakash Kanjariya, Asha Rajiv, Aman Shankhyan, Helen Merina Albert, Abdur Rahim, Vineet Tirth, Ali Algahtani, Li Zhengxin, Muslim Khan, Ruqia Nazir
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Abstract

In this work, we have developed a novel and sensitive colorimetric sensor by the constructions of hierarchical star-like structure of exfoliated NiO called as NiO-ɤ catalyst with strong peroxidase mimetic properties. The as prepared sensor predicted highest sensing response with wider and linear range of 0.001-0.900 µM, having limit of detection (LOD) and limit of quantification (LOQ) values of 0.09 ± 0.05 nM and 0.63 ± 0.05 nM. In addition, it also manifests astonishing selectivity, ample stability, better reproducibility and excellent practicality. Thus, as a result we concluded that this method is simple, robust, color stable and reliable, and hence provides an effective colorimetric bio-sensing platform for biomedical-diagnosis.

具有极好的过氧化物酶模拟性能的NiO纳米片的层次型星形结构的构建,用于有效的比色H2O2传感。
在这项工作中,我们开发了一种新的灵敏的比色传感器,通过构建分层星形结构的剥离NiO,称为NiO- o催化剂,具有强的过氧化物酶模拟性质。该传感器的检测响应范围为0.001 ~ 0.900µM,线性范围较宽,检测限(LOD)和定量限(LOQ)分别为0.09±0.05 nM和0.63±0.05 nM。此外,它还表现出惊人的选择性、充足的稳定性、较好的重现性和优异的实用性。结果表明,该方法简便、鲁棒性好、颜色稳定可靠,为生物医学诊断提供了有效的比色生物传感平台。
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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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