Evaluating the Performance of the Modified Mini-Mental State Examination for Children (MMSEc) to Screen for Intellectual Disability in Children With and Without Epilepsy.
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Abstract
The Modified Mini-Mental State Examination for Children (MMSEc) is a screening tool for identifying intellectual disabilities in children. This study compares MMSEc scores with Full-Scale Intelligence Quotient (FSIQ) scores in 6-14-year-old children with epilepsy (n = 56) and controls with no neurologic disorders (n = 56). A positive correlation was observed between FSIQ and MMSEc scores (Spearman r = 0.873; P < .001). The MMSEc demonstrated a sensitivity of 77.08%, specificity of 100%, positive predictive value of 100%, negative predictive value of 42.11%, and an overall accuracy of 80.35% in identifying children with an FSIQ lower than 70. The area under the receiver operating characteristic curve was 0.993, with the optimal MMSEc threshold score being 22. MMSEc scores were low (<2 SD) for age-defined norms in 66.1% of children with epilepsy. The MMSEc could potentially be a quick and useful tool to screen for intellectual disability in children.
期刊介绍：
The Journal of Child Neurology (JCN) embraces peer-reviewed clinical and investigative studies from a wide-variety of neuroscience disciplines. Focusing on the needs of neurologic patients from birth to age 18 years, JCN covers topics ranging from assessment of new and changing therapies and procedures; diagnosis, evaluation, and management of neurologic, neuropsychiatric, and neurodevelopmental disorders; and pathophysiology of central nervous system diseases.
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