Shortwave infrared imaging increases the number of lymph nodes and improves cancer staging: a 104-patient study.

IF 2 4区医学 Q2 PATHOLOGY

Journal of Clinical Pathology Pub Date : 2025-08-24 DOI:10.1136/jcp-2024-210038

Julie M Jorns, Randall S Smith, Dennis Strenk, Greg Stauble, Sihem Khelifa, Ryan Seltzer, John Manuel, Matthew W Rosenbaum, James Almas, Zhongming Li

{"title":"Shortwave infrared imaging increases the number of lymph nodes and improves cancer staging: a 104-patient study.","authors":"Julie M Jorns, Randall S Smith, Dennis Strenk, Greg Stauble, Sihem Khelifa, Ryan Seltzer, John Manuel, Matthew W Rosenbaum, James Almas, Zhongming Li","doi":"10.1136/jcp-2024-210038","DOIUrl":null,"url":null,"abstract":"Aims: Adequate lymph node examination is key to accurate cancer staging. This study investigates the effectiveness of shortwave infrared imaging in increasing the overall and positive lymph node numbers.Methods: Specimens from various anatomic sites, including colorectal, pancreatic, breast, gastric, skin and small bowel resections, were evaluated. 104 specimens were first grossed with manual palpation and then grossed with the assistance of shortwave infrared imaging. The overall and positive lymph node numbers were documented.Results: In 90 of the 104 cases (86.5%), shortwave infrared imaging helped identify additional lymph nodes. On average, 4.81 additional lymph nodes were found. In 11 of the 104 cases (10.6%), additional positive lymph nodes were found. In 4 of the 104 cases (3.8%), cancer stages were changed.Conclusions: Shortwave infrared imaging may increase the number of lymph nodes identified and has the potential to improve cancer staging accuracy. Further validation in larger, randomised or prospective studies is warranted.","PeriodicalId":15391,"journal":{"name":"Journal of Clinical Pathology","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/jcp-2024-210038","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PATHOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: Adequate lymph node examination is key to accurate cancer staging. This study investigates the effectiveness of shortwave infrared imaging in increasing the overall and positive lymph node numbers.

Methods: Specimens from various anatomic sites, including colorectal, pancreatic, breast, gastric, skin and small bowel resections, were evaluated. 104 specimens were first grossed with manual palpation and then grossed with the assistance of shortwave infrared imaging. The overall and positive lymph node numbers were documented.

Results: In 90 of the 104 cases (86.5%), shortwave infrared imaging helped identify additional lymph nodes. On average, 4.81 additional lymph nodes were found. In 11 of the 104 cases (10.6%), additional positive lymph nodes were found. In 4 of the 104 cases (3.8%), cancer stages were changed.

Conclusions: Shortwave infrared imaging may increase the number of lymph nodes identified and has the potential to improve cancer staging accuracy. Further validation in larger, randomised or prospective studies is warranted.

查看原文本刊更多论文

短波红外成像增加淋巴结数量，改善癌症分期：一项104例患者的研究。

目的：充分的淋巴结检查是肿瘤准确分期的关键。本研究探讨短波红外成像在增加淋巴结总数和阳性数目方面的有效性。方法：对结肠、胰腺、乳腺、胃、皮肤、小肠等不同解剖部位的标本进行评价。104例标本先采用手触诊法，再辅以短波红外成像法。记录了总体和阳性淋巴结数目。结果：在104例中，90例（86.5%）短波红外成像有助于发现额外的淋巴结。平均新增4.81个淋巴结。104例中有11例（10.6%）伴有淋巴结阳性。104例中有4例（3.8%）改变了癌症分期。结论：短波红外成像可能会增加淋巴结的识别数量，并有可能提高癌症分期的准确性。需要在更大规模、随机或前瞻性研究中进一步验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Clinical Pathology 医学-病理学

CiteScore

7.80

自引率

2.90%

发文量

113

审稿时长

3-8 weeks

期刊介绍： Journal of Clinical Pathology is a leading international journal covering all aspects of pathology. Diagnostic and research areas covered include histopathology, virology, haematology, microbiology, cytopathology, chemical pathology, molecular pathology, forensic pathology, dermatopathology, neuropathology and immunopathology. Each issue contains Reviews, Original articles, Short reports, Correspondence and more.