Changes in optical coherence tomography (OCT) parameters in follow-up of acute posterior multifocal placoid pigment epitheliopathy (APMPPE).

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2025-08-22 DOI:10.1007/s10792-025-03718-9

Burcu Kemer Atik, Ibrahim Uzar, Cigdem Altan, Berru Yargi Ozkocak, Berna Basarir

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引用次数: 0

Abstract

Purpose: To investigate retinal and choroidal optical coherence tomography (OCT) parameters in eyes with acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and their changes during the follow-up.

Methods: Best corrected visual acuity (BCVA- Snellen), central macular thickness (CMT), central choroidal thickness (CCT), total choroidal area (TCA), and choroidal vascularity index (CVI) and the other clinical findings were recorded at baseline and month 1, month 3, and year 1.

Results: Twenty-two eyes of 11 patients were included in this study. The mean follow-up period was 18.3 ± 11.9 months. While the mean BCVA value was 0.54 at the initial visit; it improved statistically significantly to 0.74 at the 3rd-month visit (p = 0.025). The highest levels of CMT, CCT, TCA and CVI were at baseline. Statistically significant decreases were observed in CMT at month 3 and in choroidal parameters at month 1 (p < 0.05, for each). Baseline and 1-year CMT values were positively correlated with 1-year BCVA (p = 0.001, r = 0.80 and p = 0.013, r = 0.67; respectively).

Conclusion: The acute phase of APMPPE disease is associated with increased retinal thickness and choroidal thickness, area, and vascularity. These parameters, which can be obtained non-invasively, can be valuable in the follow-up period.

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光学相干断层扫描（OCT）参数在急性后路多灶性placoid pigment epithelial opathy （APMPPE）随访中的变化。

目的：探讨急性后路多灶类胎盘色素上皮病（APMPPE）眼视网膜和脉络膜光学相干断层扫描（OCT）参数及其随访期间的变化。方法：记录两组患者的最佳矫正视力（BCVA- Snellen）、黄斑中央厚度（CMT）、脉络膜中央厚度（CCT）、脉络膜总面积（TCA）、脉络膜血管指数（CVI）及其他临床表现，分别于基线、第1个月、第3个月和第1年。结果：纳入11例患者22只眼。平均随访时间18.3±11.9个月。初诊时平均BCVA值为0.54；在第三个月的随访中，该指数显著提高至0.74 （p = 0.025）。CMT、CCT、TCA和CVI的最高水平均在基线水平。在第3个月时CMT和第1个月时脉络膜参数有统计学意义的下降(p)。结论：APMPPE疾病的急性期与视网膜厚度、脉络膜厚度、面积和血管密度增加有关。这些参数可以无创地获得，在随访期间很有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.