A handheld rapid infuser device effectively delivers blood products in the management of life-threatening anemia in 6 dogs.

IF 1.8 2区 农林科学 Q2 VETERINARY SCIENCES
Tyler Lawnichak, Adesola Odunayo, Avin Arjoonsingh, Vicki Moore
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引用次数: 0

Abstract

Objective: To describe the use of a handheld rapid infuser for the delivery of blood products to anemic dogs in shock.

Animals: 6 dogs that received a packed RBC (pRBC) transfusion with the use of a handheld rapid infuser from August 9, 2023, to April 1, 2024.

Clinical presentation: 6 dogs with a median age of 7.5 years and median body weight of 33 kg presenting with hemodynamic instability due to various causes of life-threatening anemia.

Results: The most common reason for transfusion was hemoperitoneum (4 of 6). A median volume of 7.3 mL/kg (range, 4.5 to 10 mL/kg) of pRBCs was delivered over 3.5 minutes (range, 2 to 5 minutes). Five dogs met the criteria for a massive blood transfusion, with a median transfusion rate of 2.13 mL/kg/min (range, 1 to 3.3 mL/kg/min). The post-transfusion median heart rate decreased to 97 beats/min (BPM; IQR, 89 to 99 BPM) from 155 BPM (IQR, 145 to 170 BPM), while the post-transfusion median systolic blood pressure improved to 119.5 mm Hg (IQR, 112 to 127.59 mm Hg) from 76 mm Hg (IQR, 66 to 80 mm Hg). Two dogs were discharged from the hospital, 2 dogs were euthanized, and 2 dogs died. One of the dogs that was discharged from the hospital died at home 3 days later.

Clinical relevance: The handheld infuser enabled the rapid delivery of pRBCs to dogs with life-threatening anemia, improved perfusion parameters, and resulted in no overt complications during or immediately following the transfusion. Preliminary information suggests that the device can be helpful in administering pRBCs to hemodynamically unstable large-breed dogs. Low survival rates were noted due to clinical severity of diseases and euthanasia.

手持快速输液器设备有效地提供血液制品,以管理6只狗的危及生命的贫血。
目的:描述使用手持式快速输液器输送血液制品贫血狗休克。动物:从2023年8月9日至2024年4月1日,6只狗使用手持式快速输液器接受了红细胞(pRBC)输血。临床表现:6只狗,中位年龄7.5岁,中位体重33公斤,由于各种原因导致危及生命的贫血,血流动力学不稳定。结果:腹腔积血是最常见的输血原因(4 / 6)。红细胞的中位体积为7.3 mL/kg(范围,4.5至10 mL/kg),递送时间为3.5分钟(范围,2至5分钟)。5只狗符合大量输血标准,平均输血率为2.13 mL/kg/min(范围为1 ~ 3.3 mL/kg/min)。输血后中位心率从155次/分钟(IQR, 145 ~ 170次/分钟)降至97次/分钟(BPM; IQR, 89 ~ 99次/分钟),输血后中位收缩压从76毫米汞柱(IQR, 66 ~ 80毫米汞柱)降至119.5毫米汞柱(IQR, 112 ~ 127.59毫米汞柱)。2只狗出院,2只狗安乐死,2只狗死亡。其中一只出院的狗3天后在家中死亡。临床意义:手持式输液器使红细胞能够快速输送到危及生命的贫血犬,改善灌注参数,并且在输血期间或输血后立即没有明显的并发症。初步信息表明,该设备可以帮助给血动力不稳定的大品种狗提供红细胞。由于疾病的临床严重性和安乐死,生存率很低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
15.80%
发文量
539
审稿时长
6-16 weeks
期刊介绍: Published twice monthly, this peer-reviewed, general scientific journal provides reports of clinical research, feature articles and regular columns of interest to veterinarians in private and public practice. The News and Classified Ad sections are posted online 10 days to two weeks before they are delivered in print.
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