Evaluation of Sexual Function and Vaginal Prolapse Relapse in Patients Undergoing Laparoscopic Sacropexy Versus Pectopexy.

IF 1.8 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
In vivo Pub Date : 2025-09-01 DOI:10.21873/invivo.14086
Mónica Isabel Herrmann, Britta Grüne, Marc Sütterlin, Sebastian Berlit, Maren Juliane Wenk
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引用次数: 0

Abstract

Background/aim: This study aimed to compare sexual function and clinical outcomes in patients undergoing laparoscopic sacropexy (LSP) versus laparoscopic pectopexy (LPP) to treat vaginal cuff or uterine prolapse.

Patients and methods: A cross-sectional explorative cohort study of 46 patients who underwent LSP (n=23) or LPP (n=23) in our tertiary care hospital was conducted. The patients' postoperative sexual function was evaluated (female sexual function index, FSFI), and prolapse stages were determined with the pelvic organ prolapse quantification system (POP-Q).

Results: Both groups showed comparable baseline parameters. Mean age was higher in the LSP group (66.76 vs. 61.30 years, p=0.14). The operation time was slightly longer in the LPP group (118 vs. 109 min, p=0.12). Uterus preservation was more common in LPP (p=0.02). There were a few low-grade complications [two patients LPP, one patient LSP, Clavien-Dindo-Classification (CDC) I and II, p=1.00], but no complications of ≥CDC III. Postoperative POP-Q results were comparable for both groups (p>0.05 in all parameters). The FSFI showed similar postoperative results in both groups with a slightly higher total score for the LPP cohort, even though not significant (1.60 vs. 1.40 LSP vs. LPP cohort; p=0.35). A multiple linear regression analysis was performed, however no factors influencing postoperative sexual function were identified.

Conclusion: A comparable efficacy of apical fixation was found for LSP and LPP, complications were low in both groups, and the FSFI-results were comparable with slightly better results in the LPP group. Therefore, LPP seems to be a viable and safe alternative in the treatment of POP.

Abstract Image

Abstract Image

Abstract Image

腹腔镜骶骨固定术与胸骨固定术患者性功能及阴道脱垂复发的比较。
背景/目的:本研究旨在比较腹腔镜下骶骨固定术(LSP)与腹腔镜下胸腔镜固定术(LPP)治疗阴道袖带或子宫脱垂患者的性功能和临床结果。患者和方法:对我院三级医院46例接受LSP (n=23)或LPP (n=23)的患者进行横断面探索性队列研究。术后评估患者的性功能(女性性功能指数,FSFI),用盆腔器官脱垂量化系统(POP-Q)确定脱垂分期。结果:两组的基线参数具有可比性。LSP组患者平均年龄较高(66.76岁比61.30岁,p=0.14)。LPP组手术时间稍长(118 vs 109 min, p=0.12)。子宫保留在LPP中更为常见(p=0.02)。低级别并发症较少[2例LPP, 1例LSP, Clavien-Dindo-Classification (CDC) I和II, p=1.00],但无≥CDC III级并发症。两组术后POP-Q结果具有可比性(所有参数p < 0.05)。FSFI显示两组术后结果相似,LPP组的总得分略高,但差异无统计学意义(LSP组与LPP组的差异为1.60 vs 1.40; p=0.35)。进行多元线性回归分析,但未发现影响术后性功能的因素。结论:LSP和LPP的根尖固定效果相当,两组并发症均较低,fsfi结果相当,LPP组效果稍好。因此,LPP似乎是一种可行的和安全的替代治疗POP。
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来源期刊
In vivo
In vivo 医学-医学:研究与实验
CiteScore
4.20
自引率
4.30%
发文量
330
审稿时长
3-8 weeks
期刊介绍: IN VIVO is an international peer-reviewed journal designed to bring together original high quality works and reviews on experimental and clinical biomedical research within the frames of physiology, pathology and disease management. The topics of IN VIVO include: 1. Experimental development and application of new diagnostic and therapeutic procedures; 2. Pharmacological and toxicological evaluation of new drugs, drug combinations and drug delivery systems; 3. Clinical trials; 4. Development and characterization of models of biomedical research; 5. Cancer diagnosis and treatment; 6. Immunotherapy and vaccines; 7. Radiotherapy, Imaging; 8. Tissue engineering, Regenerative medicine; 9. Carcinogenesis.
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