Mónica Isabel Herrmann, Britta Grüne, Marc Sütterlin, Sebastian Berlit, Maren Juliane Wenk
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引用次数: 0
Abstract
Background/aim: This study aimed to compare sexual function and clinical outcomes in patients undergoing laparoscopic sacropexy (LSP) versus laparoscopic pectopexy (LPP) to treat vaginal cuff or uterine prolapse.
Patients and methods: A cross-sectional explorative cohort study of 46 patients who underwent LSP (n=23) or LPP (n=23) in our tertiary care hospital was conducted. The patients' postoperative sexual function was evaluated (female sexual function index, FSFI), and prolapse stages were determined with the pelvic organ prolapse quantification system (POP-Q).
Results: Both groups showed comparable baseline parameters. Mean age was higher in the LSP group (66.76 vs. 61.30 years, p=0.14). The operation time was slightly longer in the LPP group (118 vs. 109 min, p=0.12). Uterus preservation was more common in LPP (p=0.02). There were a few low-grade complications [two patients LPP, one patient LSP, Clavien-Dindo-Classification (CDC) I and II, p=1.00], but no complications of ≥CDC III. Postoperative POP-Q results were comparable for both groups (p>0.05 in all parameters). The FSFI showed similar postoperative results in both groups with a slightly higher total score for the LPP cohort, even though not significant (1.60 vs. 1.40 LSP vs. LPP cohort; p=0.35). A multiple linear regression analysis was performed, however no factors influencing postoperative sexual function were identified.
Conclusion: A comparable efficacy of apical fixation was found for LSP and LPP, complications were low in both groups, and the FSFI-results were comparable with slightly better results in the LPP group. Therefore, LPP seems to be a viable and safe alternative in the treatment of POP.
期刊介绍:
IN VIVO is an international peer-reviewed journal designed to bring together original high quality works and reviews on experimental and clinical biomedical research within the frames of physiology, pathology and disease management.
The topics of IN VIVO include: 1. Experimental development and application of new diagnostic and therapeutic procedures; 2. Pharmacological and toxicological evaluation of new drugs, drug combinations and drug delivery systems; 3. Clinical trials; 4. Development and characterization of models of biomedical research; 5. Cancer diagnosis and treatment; 6. Immunotherapy and vaccines; 7. Radiotherapy, Imaging; 8. Tissue engineering, Regenerative medicine; 9. Carcinogenesis.