Assessment of pancreatic volume in the turkish adult population using 3D Slicer-based computed tomography segmentation.

IF 1.2 4区医学 Q3 ANATOMY & MORPHOLOGY

Folia morphologica Pub Date : 2025-09-02 DOI:10.5603/fm.106117

Ece Zengin, Rasime Pelin Kavak, Behlül Atalay, İhsaniye Süer Doğan, Dilara Patat

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引用次数: 0

Abstract

Background: This study aimed to determine normative pancreatic volume (PV) values in healthy Western Asian adults using computed tomography and 3D Slicer software, and to evaluate the relationship between PV and demographic parameters including age, sex, and body mass index (BMI).

Materials and methods: A retrospective analysis was conducted on 905 adults (403 females, 502 males; mean age: 43.88 ± 17.11 years) who underwent abdominal CT between January and December 2023. Individuals with diabetes mellitus, pancreatic or peripancreatic pathology, prior malignancy, or inadequate imaging were excluded. Pancreas segmentation was manually performed on axial slices using 3D Slicer v.4.11.2, excluding ducts and vascular structures. Statistical analyses included t-tests, Pearson's correlation, and multivariate linear regression.

Results: The mean PV was 84.33 ± 5.74 cm³. Males had significantly higher PV than females (85.68 ± 6.05 cm³ vs 82.65 ± 4.83 cm³, p < 0.001). PV peaked in the fourth decade in males and the fifth decade in females, followed by a decline. A significant negative correlation between age and PV was observed in males (r = -0.321, p < 0.001), but not in females. PV positively correlated with BMI in both sexes. Age, BMI, and male sex were identified as independent predictors of PV (R² = 0.326, p < 0.001).

Conclusions: Pancreatic volume varies with age, sex, and BMI in healthy Western Asian adults. These normative values may assist in future clinical and radiological evaluations of pancreatic morphology.

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使用基于三维切片机的计算机断层扫描分割评估土耳其成人胰腺体积。

背景：本研究旨在通过计算机断层扫描和3D切片软件确定健康西亚成年人的正常胰腺体积（PV）值，并评估PV与人口统计学参数（包括年龄、性别和体重指数（BMI））之间的关系。材料与方法：对2023年1 - 12月行腹部CT检查的905例成人（女性403例，男性502例，平均年龄43.88 ± 17.11岁）进行回顾性分析。排除患有糖尿病、胰腺或胰腺周围病变、既往恶性肿瘤或影像学检查不充分的患者。使用3D Slicer v.4.11.2在轴向切片上手动进行胰腺分割，排除导管和血管结构。统计分析包括t检验、Pearson相关检验和多元线性回归。结果：平均PV为84.33 ± 5.74 cm³。男性的PV明显高于女性（85.68 ± 6.05 cm³vs 82.65 ± 4.83 cm³，p ）结论：健康的西亚成年人胰腺体积随年龄、性别和BMI而变化。这些标准值可能有助于未来胰腺形态学的临床和放射学评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Folia morphologica ANATOMY & MORPHOLOGY-

CiteScore

2.40

自引率

0.00%

发文量

218

审稿时长

6-12 weeks

期刊介绍： "Folia Morphologica" is an official journal of the Polish Anatomical Society (a Constituent Member of European Federation for Experimental Morphology - EFEM). It contains original articles and reviews on morphology in the broadest sense (descriptive, experimental, and methodological). Papers dealing with practical application of morphological research to clinical problems may also be considered. Full-length papers as well as short research notes can be submitted. Descriptive papers dealing with non-mammals, cannot be accepted for publication with some exception.