Determinants of quality of life among lung cancer patients: insights from a cross-sectional study.

IF 3.7 3区医学 Q1 CLINICAL NEUROLOGY

European Archives of Psychiatry and Clinical Neuroscience Pub Date : 2025-08-28 DOI:10.1007/s00406-025-02086-w

Theresa Halms, Martina Strasser, Alkomiet Hasan, Tobias Rüther, Andrea Rabenstein, Martin Trepel, Stephan Raab, Marcus Gertzen

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引用次数: 0

Abstract

Purpose: Lung cancer (LC) is a leading cause of cancer-related mortality, with smoking being a major risk factor. Despite the benefits of smoking cessation, many LC patients continue to smoke, potentially impacting their quality of life (QoL). This study aimed to explore factors influencing QoL among LC patients, with a focus on smoking status and mental health.

Methods: A cross-sectional study was conducted at the University Hospital of Augsburg from December 2021 to December 2023. A total of 56 LC patients were categorized into active smokers (AS), ex-smokers (ES), or never-smokers (NS). Participants completed validated questionnaires assessing QoL, depression, anxiety, stress, borderline personality disorder symptoms, and pain. Statistical analyses, including one-way ANOVA and Pearson's correlation, were employed to examine group differences and the relationship between QoL and mental health factors.

Results: No significant differences in overall QoL were observed among AS, ES, and NS. However, mental health indicators-including depression, anxiety, stress, and borderline personality disorder symptoms-were significantly negatively correlated with QoL across all groups. Pain was also a key factor affecting QoL. These findings suggest that while smoking cessation is critical for improving prognosis in LC patients, mental health and pain management are more pivotal in determining QoL.

Conclusion: This study emphasizes the need for a holistic approach to LC patient care, addressing both physical and mental health. Future research should focus on longitudinal studies to better understand the long-term effects of smoking and other influencing factors on QoL in this patient population.

查看原文本刊更多论文

肺癌患者生活质量的决定因素：来自横断面研究的见解。

目的：肺癌（LC）是癌症相关死亡的主要原因，吸烟是主要的危险因素。尽管戒烟有好处，但许多LC患者继续吸烟，潜在地影响他们的生活质量（QoL）。本研究旨在探讨影响LC患者生活质量的因素，重点关注吸烟状况和心理健康状况。方法：于2021年12月至2023年12月在奥格斯堡大学医院进行横断面研究。56例LC患者分为活跃吸烟者（AS）、戒烟者（ES）和从不吸烟者（NS）。参与者完成了评估生活质量、抑郁、焦虑、压力、边缘型人格障碍症状和疼痛的有效问卷。统计分析采用单因素方差分析和Pearson相关分析，检验组间差异及生活质量与心理健康因素的关系。结果：AS组、ES组和NS组的总体生活质量无显著差异。然而，心理健康指标——包括抑郁、焦虑、压力和边缘型人格障碍症状——在所有组中都与生活质量呈显著负相关。疼痛也是影响生活质量的关键因素。这些发现表明，虽然戒烟对改善LC患者的预后至关重要，但心理健康和疼痛管理在决定生活质量方面更为关键。结论：本研究强调需要一个整体的方法来LC患者护理，解决身体和心理健康。未来的研究应侧重于纵向研究，以更好地了解吸烟和其他影响因素对该患者群体生活质量的长期影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Archives of Psychiatry and Clinical Neuroscience 医学-精神病学

CiteScore

8.80

自引率

4.30%

发文量

154

审稿时长

6-12 weeks

期刊介绍： The original papers published in the European Archives of Psychiatry and Clinical Neuroscience deal with all aspects of psychiatry and related clinical neuroscience. Clinical psychiatry, psychopathology, epidemiology as well as brain imaging, neuropathological, neurophysiological, neurochemical and moleculargenetic studies of psychiatric disorders are among the topics covered. Thus both the clinician and the neuroscientist are provided with a handy source of information on important scientific developments.