Safety and outcome of intravenous thrombolysis in ischemic stroke related to intracranial artery dissection.

IF 2.2 3区 医学 Q3 CLINICAL NEUROLOGY
Wen Yang, Jian-Wei Wang, Mei-Xia Zhang, Hong-Fang Chen
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引用次数: 0

Abstract

Background: The clinical efficacy of intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) associated with intracranial artery dissection (IAD) remains uncertain. This study presents a case of basilar artery dissection (BAD) in a 57-year-old Asian female patient devoid of previous risk factors for stroke who experienced a sudden onset of consciousness disturbance. The patient's clinical condition deteriorated during IVT administration, but subsequent medical intervention and rehabilitative exercises facilitated eventual recovery of daily functioning. MRI eventually identified the etiology of the patient's AIS.

Conclusion: AIS related to anterior circulation IAD may pose a relatively high risk of hemorrhagic transformation and symptom exacerbation during the early stages of IVT, but the impact on long-term prognosis remains uncertain. Consequently, further investigation is warranted to assess the safety and efficacy of IVT in such patients.

Abstract Image

Abstract Image

颅内动脉夹层相关缺血性脑卒中静脉溶栓治疗的安全性和疗效。
背景:静脉溶栓(IVT)治疗急性缺血性脑卒中(AIS)合并颅内动脉夹层(IAD)的临床疗效尚不确定。本研究报告一例基底动脉夹层(BAD),患者为57岁的亚洲女性,既往无卒中危险因素,但突然出现意识障碍。患者的临床状况在静脉注射期间恶化,但随后的医疗干预和康复锻炼促进了日常功能的最终恢复。MRI最终确定了患者AIS的病因。结论:AIS与前循环IAD相关,在IVT早期可能存在较高的出血转化和症状加重风险,但对远期预后的影响尚不确定。因此,有必要进一步研究IVT在此类患者中的安全性和有效性。
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来源期刊
BMC Neurology
BMC Neurology 医学-临床神经学
CiteScore
4.20
自引率
0.00%
发文量
428
审稿时长
3-8 weeks
期刊介绍: BMC Neurology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of neurological disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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