Umbrella review and meta-analysis of the effect of delayed and immediate pushing in the second stage of labor on neonatal outcomes.

IF 2.5 3区 医学 Q2 OBSTETRICS & GYNECOLOGY
Paula Deusa-López, Ferran Cuenca-Martínez, Vanessa Sánchez-Martínez, Núria Sempere-Rubio
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引用次数: 0

Abstract

Objective: To compare neonatal outcomes for immediate pushing and delayed pushing in the second stage of labor in women receiving epidural analgesia.

Data sources: Systematic searches in PubMed, EMBASE, Scopus, and CINAHL without restrictions by language, date of publication, or methodological quality.

Study selection: The inclusion criteria were based on methodological and clinical factors such as population (pregnant women with epidural analgesia), intervention and control (delayed versus immediate pushing), neonatal outcomes, and study design (systematic reviews).

Data extraction: The outcome measures were Apgar scores at 1 and 5 min, neonatal intensive care unit admission, prevalence of low umbilical artery cord pH, and umbilical artery cord pH. The methodological quality was analyzed using the Assessing the Methodological Study Tool for Systematic Reviews (AMSTAR) and Risk Of Bias In Systematic Reviews (ROBIS) scales, and the strength of evidence was established according to the Guidelines Advisory Committee grading criteria. For the umbilical artery cord pH variable, standardized mean differences and 95% confidence intervals were calculated and pooled in a meta-analysis using the random-effects model.

Data synthesis: Seven systematic reviews with meta-analysis were included. The results suggest no difference between groups for Apgar test scores at 5 min, nor in the rate of neonatal intensive care unit admissions. Mixed results were found for delayed pushing leading to improvements in Apgar test scores at 1 min. No statistically significant between-group differences in the umbilical artery cord pH were found. The total duration of the second stage in the delayed pushing group was not significantly correlated with the umbilical artery cord pH.

Conclusions: Delayed pushing produces at least the same neonatal outcomes as immediate pushing in healthy pregnant women receiving epidural analgesia with a single fetus in vertex presentation with a limited quality of evidence. Review registered in the International Prospective Register of Systematic Reviews PROSPERO (CRD42023397616).

对产程第二阶段延迟和即刻推入对新生儿结局影响的综述和荟萃分析。
目的:比较硬膜外镇痛在分娩第二阶段立即推压和延迟推压的新生儿结局。数据来源:系统搜索PubMed, EMBASE, Scopus和CINAHL,不受语言,出版日期或方法质量的限制。研究选择:纳入标准基于方法学和临床因素,如人群(使用硬膜外镇痛的孕妇)、干预和控制(延迟推与立即推)、新生儿结局和研究设计(系统评价)。数据提取:结局指标为1分钟和5分钟时的Apgar评分、新生儿重症监护病房入院、低脐带pH患病率和脐带pH。采用系统评价方法学研究工具评估(AMSTAR)和系统评价偏倚风险(ROBIS)量表对方法学质量进行分析,并根据指南咨询委员会分级标准建立证据强度。对于脐带pH变量,计算标准化平均差异和95%置信区间,并使用随机效应模型进行荟萃分析。数据综合:纳入7篇系统综述,并进行meta分析。结果表明,5分钟Apgar测试分数在两组之间没有差异,新生儿重症监护病房入院率也没有差异。延迟推压导致1分钟时Apgar测试分数的提高,结果喜忧参半。各组间脐带pH值差异无统计学意义。延迟推胎组第二阶段总持续时间与脐带ph无显著相关。结论:在接受硬膜外镇痛且单胎处于顶位的健康孕妇中,延迟推胎与立即推胎的新生儿结局至少相同,但证据质量有限。该综述已在普洛斯彼罗国际前瞻性系统综述注册(CRD42023397616)中注册。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.70
自引率
15.40%
发文量
493
审稿时长
1 months
期刊介绍: Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report". The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.
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