Linear Focal Elastosis: What We Know From Epidemiological Studies

IF 1.8 4区 医学 Q2 DERMATOLOGY
Tim Aung, Rowland Noakes, Kais Kasem, Dedee F. Murrell
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Abstract

Linear focal elastosis (LFE), characterised by horizontal streaks on the lower back, is a dermatological condition with unclear etiopathogenesis and limited epidemiological data. This study synthesises case reports to elucidate demographic patterns, clinical manifestations, and potential associations. A literature search across PubMed, Embase, Ovid and ResearchGate identified 37 relevant articles, yielding 80 cases after excluding duplicates and irrelevant articles. In analysis, the male-to-female ratio for LFE was 5:1, with a mean age of 39 years. Cases were more common among adolescents and older adults (age ≥ 60), with the majority occurring in pubertal adolescents. No racial predilection was observed. The lower back was the most frequently affected site, with rare cases involving other body parts. Some cases were associated with growth spurts or strenuous exercise, although the etiopathogenesis remains speculative. LFE may be underreported due to its asymptomatic nature and resemblance to other skin conditions, particularly striae distensae. Further research is required to clarify its pathogenesis and explore potential treatment options.

Abstract Image

线性局灶性弹性病:我们从流行病学研究中了解到的。
线性局灶性弹性病(LFE),其特征是腰部出现水平条纹,是一种病因不明且流行病学资料有限的皮肤病。本研究综合病例报告阐明人口统计模式、临床表现和潜在关联。在PubMed、Embase、Ovid和ResearchGate上进行文献检索,发现了37篇相关文章,在排除重复和不相关的文章后,得出80例病例。在分析中,LFE的男女比例为5:1,平均年龄39岁。病例在青少年和老年人(≥60岁)中更为常见,大多数发生在青春期青少年。没有观察到种族偏好。下背部是最常受影响的部位,很少有病例涉及其他身体部位。有些病例与生长突增或剧烈运动有关,但其发病机制尚不明确。由于其无症状性和与其他皮肤状况(特别是扩张纹)相似,LFE可能被低估。需要进一步的研究来阐明其发病机制并探索潜在的治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.20
自引率
5.00%
发文量
186
审稿时长
6-12 weeks
期刊介绍: Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society, publishing peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology. Clinical presentations, medical and physical therapies and investigations, including dermatopathology and mycology, are covered. Short articles may be published under the headings ‘Signs, Syndromes and Diagnoses’, ‘Dermatopathology Presentation’, ‘Vignettes in Contact Dermatology’, ‘Surgery Corner’ or ‘Letters to the Editor’.
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