{"title":"Determinants and implications of mobile health application acceptability in high-income countries: an assessment","authors":"Olugbenga Akiogbe , Yoshiyuki Kobayashi , Itsuki Kageyama , Nobuyuki Wakui , Yenogjoo Lim , Kota Kodama","doi":"10.1016/j.drudis.2025.104460","DOIUrl":null,"url":null,"abstract":"<div><div>Here, we synthesize evidence for the determinants influencing mobile health (mHealth) application acceptability in high-income countries. Based on a synthesis of key studies, we identify that performance expectancy, trust, effort expectancy, social influence, and facilitating conditions significantly shape user acceptance. These factors are further influenced by age, digital literacy, and motivation. Findings show that technical quality alone does not ensure adoption; successful integration requires clinical alignment, institutional trust, and user-centered design. Thus, progress in the use of mHealth applications will depend on collaboration among technologists, healthcare providers, and patients to co‑create solutions that meet both real needs and constraints.</div></div>","PeriodicalId":301,"journal":{"name":"Drug Discovery Today","volume":"30 10","pages":"Article 104460"},"PeriodicalIF":7.5000,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug Discovery Today","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1359644625001734","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Here, we synthesize evidence for the determinants influencing mobile health (mHealth) application acceptability in high-income countries. Based on a synthesis of key studies, we identify that performance expectancy, trust, effort expectancy, social influence, and facilitating conditions significantly shape user acceptance. These factors are further influenced by age, digital literacy, and motivation. Findings show that technical quality alone does not ensure adoption; successful integration requires clinical alignment, institutional trust, and user-centered design. Thus, progress in the use of mHealth applications will depend on collaboration among technologists, healthcare providers, and patients to co‑create solutions that meet both real needs and constraints.
期刊介绍:
Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed.
Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.