Recent Advances in Microneedle Technology for Skin Antiaging

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS
Bin Liu, Liping Zhao, Ziyu Wang, Chuanzhi Zhu*, Huailong Chang* and Hongqian Chu*, 
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Abstract

Microneedle (MN) technology is rapidly gaining popularity as a skin treatment option, particularly in the field of antiaging. Driven by an aging population and the increasing desire for aesthetic enhancement, the pursuit of effective solutions for skin aging has become a major focus in medical aesthetics, emphasizing the need for innovative treatments. MN technology offers a compelling alternative for creating microchannels in the skin and stimulating natural healing and regeneration processes. This approach enhances mechanical stimulation, facilitates drug delivery, restores skin vitality, and improves skin elasticity, ultimately leading to significant antiaging effects. In this review, we discuss the principles and structural features of MN technology, highlighting their relevance to the underlying mechanisms of skin aging, including mechanical structural breakdown, barrier dysfunction, and metabolic issues. We further explored the applications of MNs in dermatological treatments and analyzed clinical research to evaluate the efficacy of MN technology in addressing skin aging. Finally, we discuss the future applications and research directions of MN. Despite its considerable potential, MN technology faces several challenges, including the need for standardized treatment protocols, a comprehensive evaluation of long-term effects, and careful consideration of individual patient variations. Overcoming these issues is crucial for the broader clinical application of this promising technology.

Abstract Image

皮肤抗衰老微针技术研究进展。
微针(MN)技术作为一种皮肤治疗选择正在迅速普及,特别是在抗衰老领域。在人口老龄化和人们对美容的需求日益增长的推动下,寻求有效的皮肤衰老解决方案已成为医学美学的主要焦点,强调需要创新的治疗方法。MN技术为在皮肤中创建微通道和刺激自然愈合和再生过程提供了令人信服的替代方案。这种方法增强机械刺激,促进药物传递,恢复皮肤活力,提高皮肤弹性,最终达到显著的抗衰老效果。在这篇综述中,我们讨论了MN技术的原理和结构特征,强调了它们与皮肤老化的潜在机制的相关性,包括机械结构破坏、屏障功能障碍和代谢问题。我们进一步探讨了MN在皮肤病学治疗中的应用,并分析了临床研究,以评估MN技术在解决皮肤老化方面的疗效。最后,讨论了锰的应用前景和研究方向。尽管具有巨大的潜力,但MN技术面临着一些挑战,包括需要标准化的治疗方案,对长期效果的全面评估,以及仔细考虑个体患者的差异。克服这些问题对于这项有前途的技术的更广泛的临床应用至关重要。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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