A Case of Drug-Resistant Renovascular Hypertension due to Renal Artery Stenosis Successfully Treated by Nephrectomy of the Affected Kidney

Q4 Medicine

IJU Case Reports Pub Date : 2025-08-19 DOI:10.1002/iju5.70084

Moeto Shimoda, Shinji Otake, Masashi Imano, Tetsuya Aoki, Jurii Karibe, Yosuke Shibata, Masahiro Inoue, Akiko Nagatomo, Mayumi Yakeishi, Kazuki Kobayashi

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Abstract

Introduction

Renal artery stenosis (RAS) reduces renal blood flow and activates the renin-angiotensin-aldosterone (RAA) system, resulting in renovascular hypertension (RVH).

Case Presentation

We report a case of a 49-year-old woman with RVH due to bilateral renal artery stenosis, predominantly on the right. Despite pharmacological treatment, blood pressure remained poorly controlled; leading to severe heart failure that required dialysis. Percutaneous renal angioplasty was considered but deemed technically difficult. The patient underwent a successful laparoscopic right nephrectomy, leading to improved blood pressure control and reduced need for antihypertensive medications.

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肾动脉狭窄致耐药肾血管性高血压经肾切除术成功治疗1例

肾动脉狭窄（RAS）减少肾血流量，激活肾素-血管紧张素-醛固酮（RAA）系统，导致肾血管性高血压（RVH）。我们报告一例49岁女性因双侧肾动脉狭窄而导致的RVH，主要发生在右侧。尽管进行了药物治疗，但血压控制仍然很差；导致严重的心脏衰竭，需要透析。考虑过经皮肾血管成形术，但认为技术上困难。患者接受了成功的腹腔镜右肾切除术，改善了血压控制，减少了对降压药物的需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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