{"title":"Exploring healthcare in the 6G and AI era: Opportunities and challenges","authors":"Houssein Taleb , Guillaume Andrieux , Daniele Khalife , Alain Ajami , Abbass Nasser","doi":"10.1016/j.iot.2025.101744","DOIUrl":null,"url":null,"abstract":"<div><div>The integration of AI with emerging 6G wireless communications promises to revolutionize healthcare delivery by providing ultra-fast, reliable, and intelligent medical services. Unlike previous generations of mobile phones, 6G is expected to offer sub-millisecond latency, data rates up to terabits per second, and connectivity for more than 10 million devices per square kilometer. Together, these technologies will enable unprecedented healthcare applications, such as real-time remote robotic surgery, holographic telemedicine, and continuous monitoring using bio-nanosensors within the bio-nano-internet of things.</div><div>This survey systematically analyzes the integration of AI and 6G technologies, focusing on how their convergence will enable enhanced edge computing, federated and generative AI models, low-latency analytics for personalized treatment, predictive diagnostics, and efficient resource utilization. We present a comprehensive comparison of 5G and 6G architectures, highlighting the limitations of current systems and demonstrating how 6G advancements can address critical healthcare needs, including data throughput, mobility, and security.</div><div>Furthermore, this work identifies detailed opportunities, such as AI-powered virtual nurse assistants, AI-enhanced drug discovery accelerated by hyper-responsive 6G infrastructures, and digital twin-enabled patient simulation. Alongside these opportunities, we critically examine the technical challenges related to spectrum management in the terahertz band, the design of energy-efficient IoT devices, robust data privacy frameworks that integrate federated learning and blockchain technology, ethical considerations surrounding AI explainability, and equitable access to healthcare.</div><div>By filling gaps in the existing literature, this paper presents a comprehensive framework that combines AI and 6G, specifically designed for healthcare systems. Our findings underscore the transformative potential of this combination for achieving proactive and accessible healthcare, while outlining a roadmap for overcoming prevailing technical, ethical, and infrastructural barriers.</div></div>","PeriodicalId":29968,"journal":{"name":"Internet of Things","volume":"34 ","pages":"Article 101744"},"PeriodicalIF":7.6000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Internet of Things","FirstCategoryId":"94","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2542660525002586","RegionNum":3,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
The integration of AI with emerging 6G wireless communications promises to revolutionize healthcare delivery by providing ultra-fast, reliable, and intelligent medical services. Unlike previous generations of mobile phones, 6G is expected to offer sub-millisecond latency, data rates up to terabits per second, and connectivity for more than 10 million devices per square kilometer. Together, these technologies will enable unprecedented healthcare applications, such as real-time remote robotic surgery, holographic telemedicine, and continuous monitoring using bio-nanosensors within the bio-nano-internet of things.
This survey systematically analyzes the integration of AI and 6G technologies, focusing on how their convergence will enable enhanced edge computing, federated and generative AI models, low-latency analytics for personalized treatment, predictive diagnostics, and efficient resource utilization. We present a comprehensive comparison of 5G and 6G architectures, highlighting the limitations of current systems and demonstrating how 6G advancements can address critical healthcare needs, including data throughput, mobility, and security.
Furthermore, this work identifies detailed opportunities, such as AI-powered virtual nurse assistants, AI-enhanced drug discovery accelerated by hyper-responsive 6G infrastructures, and digital twin-enabled patient simulation. Alongside these opportunities, we critically examine the technical challenges related to spectrum management in the terahertz band, the design of energy-efficient IoT devices, robust data privacy frameworks that integrate federated learning and blockchain technology, ethical considerations surrounding AI explainability, and equitable access to healthcare.
By filling gaps in the existing literature, this paper presents a comprehensive framework that combines AI and 6G, specifically designed for healthcare systems. Our findings underscore the transformative potential of this combination for achieving proactive and accessible healthcare, while outlining a roadmap for overcoming prevailing technical, ethical, and infrastructural barriers.
期刊介绍:
Internet of Things; Engineering Cyber Physical Human Systems is a comprehensive journal encouraging cross collaboration between researchers, engineers and practitioners in the field of IoT & Cyber Physical Human Systems. The journal offers a unique platform to exchange scientific information on the entire breadth of technology, science, and societal applications of the IoT.
The journal will place a high priority on timely publication, and provide a home for high quality.
Furthermore, IOT is interested in publishing topical Special Issues on any aspect of IOT.