Association between temporalis and masseter muscle thickness and dysphagia in patients with spontaneous intracerebral hemorrhage

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Clinical Neuroscience Pub Date : 2025-09-03 DOI:10.1016/j.jocn.2025.111598

Ya-Chu Hsu , Ting-Ju Lai , You-Lin Lu , Hsing-Yu Chen , Hsiao-Ting Tsai , Tyng-Guey Wang , Shu-Mei Yang , Meng-Ting Lin

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引用次数: 0

Abstract

Objectives

The aim of this study is to investigate the association between masticatory muscle thickness and dysphagia in intracerebral hemorrhage (ICH) patients.

Materials & methods

This retrospective cohort study included patients with spontaneous ICH confirmed by brain computed tomography (CT) between June 2019 and June 2024 in a university-affiliated hospital. Temporal muscle thickness (TMT) and masseter muscle thickness (MMT) were measured on the initial brain CT. Dysphagia outcomes were assessed using NG tube retention and the Functional Oral Intake Scale (FOIS) at 1, 4, and 12 weeks post-ICH. Linear regression analyzed relationships between clinicodemographic factors, comorbidities, and TMT/MMT, while logistic regression assessed associations between TMT/MMT and dysphagia outcomes, adjusting for identified variables.

Results

A total of 412 patients (61.2 % male, mean age 63.5 years) were included in the study. The mean TMT and MMT were 5.78 ± 1.54 mm and 13.51 ± 2.67 mm, respectively. Younger age, male gender, and higher body mass index were associated with increased TMT, while similar factors, along with premorbid modified Rankin scale, were linked to higher MMT. Adjusted multivariate analysis revealed significant associations between TMT and FOIS scores at 1 and 4 weeks post-ICH, with adjusted odds ratios (ORs) of 0.54 (95 % CI 0.35–0.85) and 0.41 (95 % CI 0.2–0.82), respectively. TMT was also significantly associated with NG tube retention at 1 and 4 weeks, with adjusted odds ratios (ORs) of 0.54 (95 % CI 0.35–0.85) and 0.1 (95 % CI 0.01–0.99), respectively. No significant relationships were observed between MMT and dysphagia outcomes.

Conclusion

TMT may serve as a preliminary predictor of functional oral intake impairment in post-ICH population requiring prospective validation.

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自发性脑出血患者颞肌和咬肌厚度与吞咽困难的关系

目的探讨脑出血（ICH）患者咀嚼肌厚度与吞咽困难的关系。材料和方法本回顾性队列研究纳入了2019年6月至2024年6月在某大学附属医院通过脑计算机断层扫描（CT）确诊的自发性脑出血患者。在初始脑CT上测量颞肌厚度（TMT）和咬肌厚度（MMT）。在ich后1、4和12周，使用NG管潴留和功能性口服摄入量表（FOIS）评估吞咽困难的结局。线性回归分析了临床人口学因素、合并症和TMT/MMT之间的关系，而逻辑回归评估了TMT/MMT与吞咽困难结局之间的关系，调整了已识别的变量。结果共纳入412例患者，其中男性61.2%，平均年龄63.5岁。TMT和MMT的平均值分别为5.78±1.54 mm和13.51±2.67 mm。年龄较小、男性和较高的体重指数与TMT增加有关，而类似的因素，以及病前改良Rankin量表，与较高的MMT有关。调整后的多变量分析显示，在ich后1周和4周，TMT和FOIS评分之间存在显著关联，调整后的优势比（or）分别为0.54 （95% CI 0.35-0.85）和0.41 （95% CI 0.2-0.82）。TMT在第1周和第4周时也与NG管潴留显著相关，调整比值比（or）分别为0.54 （95% CI 0.35-0.85）和0.1 （95% CI 0.01-0.99）。MMT和吞咽困难的结果之间没有明显的关系。结论tmt可作为脑出血后人群功能性口服摄入障碍的初步预测指标，需要前瞻性验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Neuroscience 医学-临床神经学

CiteScore

4.50

自引率

0.00%

发文量

402

审稿时长

40 days

期刊介绍： This International journal, Journal of Clinical Neuroscience, publishes articles on clinical neurosurgery and neurology and the related neurosciences such as neuro-pathology, neuro-radiology, neuro-ophthalmology and neuro-physiology. The journal has a broad International perspective, and emphasises the advances occurring in Asia, the Pacific Rim region, Europe and North America. The Journal acts as a focus for publication of major clinical and laboratory research, as well as publishing solicited manuscripts on specific subjects from experts, case reports and other information of interest to clinicians working in the clinical neurosciences.