{"title":"Frontispiece: Chiral Self-Sorting of Flexible Covalent Organic Pillars for Adaptive Molecular Recognition","authors":"","doi":"10.1002/ange.202583601","DOIUrl":null,"url":null,"abstract":"<p>The cover illustrates the chiral self-sorting and adaptive host-guest behavior of <b>flex-COP-n</b>, a new family of flexible covalent organic pillars with deep-cavity architectures (e202509177). These nanotubular hosts form enantiomeric or <i>meso</i> duplexes via dynamic imine condensation and accommodate guest molecules through mutual deformation. Cartoon springs and character-filled cavities depict how host and guest adjust their shapes to achieve precise molecular recognition, echoing biological receptors.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 36","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ange.202583601","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angewandte Chemie","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ange.202583601","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The cover illustrates the chiral self-sorting and adaptive host-guest behavior of flex-COP-n, a new family of flexible covalent organic pillars with deep-cavity architectures (e202509177). These nanotubular hosts form enantiomeric or meso duplexes via dynamic imine condensation and accommodate guest molecules through mutual deformation. Cartoon springs and character-filled cavities depict how host and guest adjust their shapes to achieve precise molecular recognition, echoing biological receptors.
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