Jinghan Zhang, Jiarui Du, Song Jia, Yang Li, Hans Ågren, Paras N. Prasad, Guanying Chen
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引用次数: 0
Abstract
Chemically synthesized and optically characterized rare-earth-doped upconversion nanoparticles (UCNPs) exhibit exceptional biocompatibility and distinctive optical properties after surface functionalization, rendering them ideal substrates for in vivo diagnostic and therapeutic applications. It enables synergistic therapy that integrates photodynamic therapy with multiple treatment modalities, while its distinctive imaging capabilities allow seamless fusion of diagnosis and therapy. The cover image (DOI: 10.1002/elt2.70012) illustrates UCNPs-based composite nanomaterials that are delivered via the vasculature to the tumor microenvironment, enabling precise targeting, controlled drug release, and potent tumor eradication.
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