Highly Sensitive TiO2-Gold Coated Plasmonic Biosensor with Microchannel-Based D-shaped Photonic Crystal Fiber

IF 4.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL
Ahan Chakrabortty, Safayat-Al Imam, Md. Sazzad Ali Rafe, Md. Saif Ali Khan, Rithik Ghosh
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Abstract

A microchannel-based D-shaped photonic crystal fiber (PCF) biosensor utilizing surface plasmon resonance (SPR) to measure the refractive index (RI) of an analyte in the near-infrared (IR) region is proposed in this paper. The sensor's design incorporates a hexagonal lattice with four rings of circular air holes, where the upper row of holes is etched to create a D-shaped plane and a microchannel is integrated. The external sensing mechanism allows plasmonic gold (Au) deposition on the interior surface, with a thin titanium dioxide (TiO2) layer to improve adhesion. Numerical simulations utilizing the finite element method (FEM) with perfectly matched layer (PML) boundary conditions were employed to optimize the important parameters, executed through COMSOL Multiphysics. The simulation results indicate that the optimized sensor achieves a peak wavelength sensitivity of 23,500 nm/RIU, amplitude sensitivity of 489.3 RIU⁻1, resolution of 4 × 10⁻⁶ RIU, and FOM of 412.28 within the refractive index (RI) range of 1.31 to 1.42. With its high sensitivity, wide detection range, and fabrication tolerance, the proposed sensor shows strong potential for biological and biochemical analyte detection.

基于微通道d形光子晶体光纤的高灵敏度tio2 -金涂层等离子体生物传感器
提出了一种基于微通道的d形光子晶体光纤(PCF)生物传感器,利用表面等离子体共振(SPR)测量被分析物在近红外区域的折射率(RI)。传感器的设计结合了一个六角形晶格和四个环形空气孔,其中上面一排孔被蚀刻成一个d形平面,并集成了一个微通道。外部传感机制允许等离子体金(Au)沉积在内表面,并与薄薄的二氧化钛(TiO2)层一起提高附着力。采用COMSOL Multiphysics软件,采用完全匹配层(PML)边界条件下的有限元法(FEM)进行数值模拟,对重要参数进行优化。仿真结果表明,优化后的传感器峰值波长灵敏度为23,500 nm/RIU,幅值灵敏度为489.3 RIU - 1,分辨率为4 × 10⁻26 RIU,在折射率(RI)为1.31 ~ 1.42范围内的FOM为412.28。该传感器具有高灵敏度、宽检测范围和制造公差,在生物和生化分析物检测中具有很强的潜力。
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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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